Clostridium ihumii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium ihumii is a Gram-positive, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 26.7%. Clostridium ihumii is probably a rare gut coloniser. (Merhej2015; Pfleiderer2018)



  • This organism has been recovered from human faeces (Merhej2015). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Merhej2015); (Pfleiderer2018);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; gelatin;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 45℃; Grows optimally at 37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; glucose;
  • Active enzymes:
  • Ala arylamidase; alkaline phosphatase; acid phosphatase; Arg arylamidase; arginine dihydrolase; N-Ac β-glucosaminidase; esterase; esterase lipase C8; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase; glutamic acid decarboxylase; Gly arylamidase; His arylamidase; Leu arylamidase; Leu-Gly arylamidase; lipase C14; α-mannosidase; oxidase; Phe arylamidase; Pro arylamidase; pyroGlu arylamidase; Tyr arylamidase;
    • SPECIAL FEATURES (Merhej2015);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Merhej2015);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; imipenem;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (Merhej2015)
    DNA G+C(%):  26.7
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  45(+)
    		Aesculin:  + Gelatin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  + Glucose:  + Mannose:  neg Maltose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  neg Urease:  neg Ac-β-glcamnd:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + α-Mannosidase:  + ArgDH:  + GluDC:  + AlanineAA:  + ArgAA:  + GlyAA:  + HisAA:  + LeuAA:  + LeuGlyAA:  + ProAA:  + PheAA:  + PyrogluAA:  + TyrAA:  + AlkalineP:  + AcidP:  + Esterase:  + EstLip(C8):  + Lipase(C14):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    imipenem:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens
    rifampicin:  Sens
    metronidazole:  Sens
    SXT:  Res

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM IHUMII
  • Merhej2015 - Non-contiguous finished genome sequence and description of Clostridium ihumii sp. nov.
  • Pfleiderer2018 - Diversität Der Intestinalen Mikrobiota Am Beispiel Der Darmflora Einer Anorexia Patientin.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM IHUMII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • GENERAL REFERENCES FOR CLOSTRIDIUM IHUMII
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: July 12, 2021