Clostridium intestinale

(aka Clostridium intestinalis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium intestinale, (aka Clostridium intestinalis), is a Gram-positive, spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 26-28%. Clostridium intestinale is probably a rare gut coloniser. (Rainey2011aBergey; Elsayed2005; Lee1989)



  • This organism has been recovered from pig, cattle faeces and human large intestine (Elsayed2005). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Rainey2011aBergey); (Elsayed2005); (Lee1989);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; trehalose; mannitol; sorbitol;
  • ⥅
  • Substrates assimilated or utilised:
  • amygdalin; cellubiose; fructose; galactose; glucose; lactose; mannitol; mannose; salicin; sorbitol; sucrose; trehalose;
    • SPECIAL FEATURES (Rainey2011aBergey); (Elsayed2005); (Lee1989);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate (minor); lactate (minor); isobutyrate (minor); isovalerate (minor); H₂ (minor);
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • Haemolysis:
  • beta
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Alt. name:  Clostridium intestinalis Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  pig, cattle faeces and human large intestine (Elsayed2005)
    DNA G+C(%):  26-28
    Opt. T:  37℃
    		Aesculin:  + Starch:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  + Maltose:  neg Trehalose:  + Starch:  neg Mannitol:  + Sorbitol:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  neg Cellubiose:  + Lactose:  + Maltose:  neg Melezitose:  neg Melibiose:  neg Raffinose:  neg Sucrose:  + Trehalose:  + Adonitol:  neg Amygdalin:  + Dulcitol:  neg Erythritol:  neg Aesculin:  neg Glycerol:  neg Glycogen:  neg Inositol:  neg Inulin:  neg Mannitol:  + Salicin:  + Sorbitol:  + Starch:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  minor(+) Lactate:  minor(+) Isobutyrate:  minor(+) Isovalerate:  minor(+) H2S:  neg H2:  minor(+) Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM INTESTINALE
  • Rainey2011aBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster I
  • Elsayed2005 - Bacteremia caused by Clostridium intestinale.
  • Lee1989 - Clostridium intestinalis sp. nov., an Aerotolerant Species Isolated from the Feces of Cattle and Pigs.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM INTESTINALE
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • GENERAL REFERENCES FOR CLOSTRIDIUM INTESTINALE
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 22, 2021