General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview


  • Clostridium magnum is a Gram-negative, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 29.1%. Clostridium magnum is probably a rare gut coloniser. (Rainey2011aBergey; Schink2004)



  • This organism has been recovered from anoxic freshwater sediments. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.

  • QUIRKS
  • Homoacetogen.

  • GENERAL CHARACTERISTICS (Rainey2011aBergey); (Schink2004);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-7.5; Grows optimally at pH 7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 45℃; Grows optimally at 30-32℃.
  • Substrates assimilated or utilised:
  • fructose; glucose; sucrose; xylose; citrate; malate; pyruvate;

  • SPECIAL FEATURES (Rainey2011aBergey); (Schink2004);
    Character Response
  • Metabolites produced:
  • acetate; Hâ‚‚;
  • Nitrate:
  • not reduced
  • Sulfate:
  • not reduced
  • Thiosulfate:
  • not reduced

  • Details


    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Clostridiales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  anoxic freshwater sediments
    DNA G+C(%):  29.1
    Opt. T:  30-32℃
    Low T(℃):  15(+)
    High T(℃):  45(+)
    Opt. pH:  7.0
    pH 6.0-8.0:  6.0-7.5(+)
    Urea:  neg Gelatin:  neg

    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Glucose:  + Ribose:  neg Xylose:  + Maltose:  neg Sucrose:  + Ethanol:  neg Glycerol:  neg Methanol:  neg Starch:  neg Ser:  neg Acetate:  neg Citrate:  + Fumarate:  neg Glycerate:  neg Glycolate:  neg Lactate:  neg Malate:  + Pyruvate:  +

    References


    SPECIFIC REFERENCES FOR CLOSTRIDIUM MAGNUM
  • Rainey2011aBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster I
  • Schink2004 - Clostridium magnum sp. nov., a non-autotrophic homoacetogenic bacterium.
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  • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM MAGNUM
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
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