Clostridium nitritogenes

(aka Eubacterium nitritogenes)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium nitritogenes, (aka Eubacterium nitritogenes), is a Gram-positive, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. Clostridium nitritogenes is probably a rare gut coloniser. (Bernard2018)



  • This organism has been recovered from human faeces, soil and clinical sources (infections). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Can cause opportunistic infections, particularly in immunocompromised people. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Bernard2018);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; ribose; cellubiose; maltose; sucrose; trehalose; salicin;
    • SPECIAL FEATURES (Bernard2018);
    Character Response
  • ✓
  • Metabolites produced:
  • butyrate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚; indole;
  • ✓
  • Nitrate:
  • reduced

  • Finegold, S. M., Howard, R. A., & Vera, L. S. (1974). Effect of diet on human intestinal fecal flora: comparison of Japanese and American diets. Am. J. Clin. Nutr, 27, 1456–1469.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Alt. name:  Eubacterium nitritogenes Gram stain:  + O2 Relation.:  strictly anaerobic Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, soil and clinical sources (infections)
    		Aesculin:  neg Gelatin:  neg Starch:  neg Milk:  neg Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  w(+) Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  d(+) Cellubiose:  w(+) Lactose:  neg Maltose:  w(+) Melezitose:  neg Melibiose:  neg Sucrose:  d(+) Trehalose:  d(+) Amygdalin:  neg Aesculin:  neg Glycogen:  neg Starch:  neg Mannitol:  neg Sorbitol:  neg Salicin:  d(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Butyrate:  + H2:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM NITRITOGENES
  • Bernard2018 - Clostridium neonatale sp. nov. linked to necrotizing enterocolitis in neonates and a clarification of species assignable to the genus Clostridium (Prazmowski 1880) emend. Lawson and Rainey 2016.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM NITRITOGENES
  • Finegold1974 - Effect of diet on human fecal flora: comparison of Japanese and American diets
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • ...............................
    • GENERAL REFERENCES FOR CLOSTRIDIUM NITRITOGENES
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021