Clostridium pasteurianum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium pasteurianum is a Gram-positive, spore-forming, anaerobic, variably-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 26-28%. Clostridium pasteurianum is probably a rare gut coloniser. (Rainey2011aBergey)



  • This organism has been recovered from soil. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Rainey2011aBergey);
    Character Response
  • Substrates hydrolysed or digested:
  • DNA;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 6.5% salt;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • gluconate;
  • ⥅
  • Substrates assimilated or utilised:
  • fructose; maltose; mannitol; mannose; melezitose; melibiose; raffinose; sorbitol; sucrose; trehalose; N2 fixed; NH4+ consumed;
  • Active enzymes:
  • DNase;
    • SPECIAL FEATURES (Rainey2011aBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • formate (minor); acetate; butyrate; ethanol; CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • H₂S; ammonia; indole;
  • ✓
  • VP test:
  • active
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Rainey2011aBergey);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  anaerobic Spore:  Endospore Motility:  vr Morphology:  Rod
    Health:  Unknown
    Source:  soil
    DNA G+C(%):  26-28
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  45(neg)
    NaCl >6%:  6.5(neg)
    pH >8:  8.5(neg)
    Bile reaction(%):  20(neg)
    		Aesculin:  neg DNA:  + Milk:  neg Meat:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Gluconate:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  w Fructose:  + Galactose:  w Mannose:  + Rhamnose:  neg Ribose:  neg Xylose:  w Lactose:  w Maltose:  + Melezitose:  + Melibiose:  + Raffinose:  + Sucrose:  + Trehalose:  + Amygdalin:  neg Glycogen:  neg Inulin:  neg Mannitol:  + Salicin:  neg Sorbitol:  + Starch:  w Thr:  neg Pyruvate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    DNAse:  + Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  minor(+) Acetate:  + Butyrate:  + Ethanol:  + H2S:  neg Ammonia:  neg CO2:  + H2:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  Sens
    erythromycin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Sens
    chloramphenicol:  Sens
    clindamycin:  Sens

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM PASTEURIANUM
  • Rainey2011aBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster I
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM PASTEURIANUM
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: March 18, 2022