Clostridium phoceensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium phoceensis is a Gram-negative, spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 59.3%. Clostridium phoceensis is probably a rare gut coloniser. (Hosny2016)



  • This organism has been recovered from human faeces (Hosny2019). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Hosny2016);
    Character Response
  • 🌡
  • Temperature tolerance:
  • grows weakly at 37℃; Grows optimally at 45℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose;
  • Active enzymes:
  • acid phosphatase; esterase C4; β-glucosidase; naphthol-ASBI-P;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Hosny2016);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; doripenem; imipenem;
  • Cephalosporins:
  • ceftazidime;
  • Quinolines:
  • ciprofloxacin;
  • NOTES

    Formerly known as Clostridium phoceensis. This is a recently discovered species that is an inhabitant of the gut microbiome. It has not been described by scientists yet. Once more information is available about this species, this description will be updated.

    Metabolites produced:
    Our genomic analysis indicates that most members of this species can produce the following metabolites: IPA, acetate, BCAAs, butyrate, propionate, cobalamin, folate, biotin.

    Metabolites consumed:
    In addition, our genomic analysis indicates that most members of this species do not consume any reported metabolites.

  • References: [1]

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (Hosny2019)
    DNA G+C(%):  59.3
    Opt. T:  45℃
    Mid T(℃):  37(w)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  neg Glucose:  + Mannose:  neg Ribose:  neg Lactose:  neg Maltose:  neg Sucrose:  neg Mannitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg β-Galactosidase:  neg β-Glucosidase:  + AlkalineP:  neg AcidP:  + Esterase(C4):  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    doripenem:  Sens
    imipenem:  Sens
    ceftazidime:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM PHOCEENSIS
  • Hosny2016 - Description of Clostridium phoceensis sp. nov., a new species within the genus Clostridium.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM PHOCEENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • ...............................
    • GENERAL REFERENCES FOR CLOSTRIDIUM PHOCEENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: March 26, 2021