Clostridium polyendosporum

(aka Anaerobacter polyendosporus)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium polyendosporum, (aka Anaerobacter polyendosporus), is a Gram-positive, spore-forming, strictly anaerobic, non-motile, pleiomorphic bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 29%. Clostridium polyendosporum is probably a rare gut coloniser. (Siunov1999; Duda1987)



  • This organism has been recovered from human faeces (probably transient) and soil. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Siunov1999); (Duda1987);
    Character Response
  • Substrates hydrolysed or digested:
  • starch;
  • pH
  • Acidity tolerance:
  • tolerates pH 5.5; tolerates pH 8.5; Grows optimally at pH 6.5-7.5.
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 45℃; Grows optimally at 25-35℃.
  • ⥅
  • Substrates assimilated or utilised:
  • cellubiose; fructose; galactose; glucose; inulin; maltose; mannitol; mannose; raffinose; salicin; sorbitol; sucrose; trehalose; xylose; lactate;
    • SPECIAL FEATURES (Duda1987);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; butyrate; lactate; ethanol; butanol; CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✓
  • Nitrite:
  • reduced
  • ✗
  • NO3➔NO2:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Duda1987);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Aminoglycosides:
  • streptomycin;
  • Polypep/ketides:
  • rifampicin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Alt. name:  Anaerobacter polyendosporus Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Sessile Morphology:  Pleiomorphic
    Health:  Unknown
    Source:  human faeces (probably transient) and soil
    DNA G+C(%):  29
    Opt. T:  25-35℃
    Low T(℃):  15(+)
    High T(℃):  45(+)
    Opt. pH:  6.5-7.5
    pH 4.2-5.9:  5.5(+)
    pH >8:  8.5(+)
    		Urea:  neg Gelatin:  neg Starch:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg Xylose:  + Cellubiose:  + Lactose:  neg Maltose:  + Raffinose:  + Sucrose:  + Trehalose:  + Cellulose:  neg Dulcitol:  neg Ethanol:  neg Glycerol:  neg Glycogen:  neg Inositol:  neg Inulin:  + Mannitol:  + Methanol:  neg Salicin:  + Sorbitol:  + Starch:  neg Butyrate:  neg Citrate:  neg Formate:  neg Lactate:  + Pyruvate:  neg Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Butyrate:  + Lactate:  + Ethanol:  + Butanol:  + H2S:  neg CO2:  + H2:  + Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  S(1)
    streptomycin:  S(1)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    rifampicin:  S(1)

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM POLYENDOSPORUM
  • Siunov1999 - Phylogenetic status of Anaerobacter polyendosporus, an anaerobic, polysporogenic bacterium.
  • Duda1987 - A new anaerobic bacterium, forming up to five endospores per cell - Anaerobacter polyendosporus gen. et spec. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM POLYENDOSPORUM
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
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    • Added: December 15, 2021