Clostridium polysaccharolyticum

(aka Fusobacterium polysaccharolyticum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium polysaccharolyticum, (aka Fusobacterium polysaccharolyticum), is a Gram-negative, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 41.6%. Clostridium polysaccharolyticum is probably a rare gut coloniser. (Rainey2011gBergey; vanGylswyk1980a; vanGylswyk1980)



  • This organism has been recovered from human faeces and sheep rumen. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Cellulolytic.
    • GENERAL CHARACTERISTICS (Rainey2011gBergey); (vanGylswyk1980a); (vanGylswyk1980);
    Character Response
  • Substrates hydrolysed or digested:
  • agar; starch; cellulose;
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 6.8.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 30-38℃.
  • H+
  • Acid from carbohydrates usually produced:
  • cellulose; starch; xylan; cellubiose;
  • ±
  • Strain-dependent acid from carbs:
  • fructose; pectin;
  • ⥅
  • Substrates assimilated or utilised:
  • acetate;
    • SPECIAL FEATURES (Rainey2011gBergey); (vanGylswyk1980);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; butyrate;
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • VP test:
  • weakly active
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Alt. name:  Fusobacterium polysaccharolyticum Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and sheep rumen
    DNA G+C(%):  41.6
    Opt. T:  30-38℃
    Opt. pH:  6.8
    		Gelatin:  neg Starch:  + Agar:  + Pectin:  w
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  w Fructose:  d Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Xylose:  w Cellubiose:  + Lactose:  neg Maltose:  w Sucrose:  neg Trehalose:  neg Cellulose:  + Inulin:  neg Starch:  + Pectin:  d(neg) Xylan:  + Glycerol:  neg Inositol:  neg Mannitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Acetate:  + DL-Lactate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Butyrate:  + H2S:  neg Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM POLYSACCHAROLYTICUM
  • Rainey2011gBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster XIVa
  • vanGylswyk1980a - Sporulation and Cell Wall Structure of Clostridium polysaccharolyticum comb. nov. (Formerly Fusobacterium polysaccharolyticum)
  • Chua2018 - Intestinal Dysbiosis Featuring Abundance of Ruminococcus gnavus Associates With Allergic Diseases in Infants
  • vanGylswyk1980 - Fusobacterium polysaccharolyticum sp.nov., a gram-negative rod from the rumen that produces butyrate and ferments cellulose and starch.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM POLYSACCHAROLYTICUM
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
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    • Added: October 28, 2021