Clostridium scatologenes

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium scatologenes is a Gram-positive, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. The DNA G+C content is 27%. Clostridium scatologenes is probably a rare gut coloniser. (Kuesel2000; Rainey2011aBergey)



  • This organism has been recovered from human faeces (undersized infants - Rainey2011aBergey). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Can cause opportunistic infections, particularly in immunocompromised people. Is a known gut commensal.
    • QUIRKS
  • Homoacetogen. Able to use the following donors: ethanol, butanol, glycerol, sugars, methoxylated aromatics.
    • GENERAL CHARACTERISTICS (Kuesel2000); (Rainey2011aBergey);
    Character Response
  • ±
  • Strain-dependent hydrolysis or digestion:
  • hippurate;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 6.5% salt;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 8.5; Grows optimally at pH 6.3.
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; doesn't grow at 45℃; Grows optimally at 30-37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • cellubiose; ethanol; fructose; gluconate; glucose; glycerol; mannose; pectin; propanol; arginine; isoleucine; leucine; serine; valine; formate; lactate; pyruvate; butanol; H2 consumed; CO2 consumed;
  • ±
  • Strain-dependent substrate utilisation:
  • rhamnose; xylose;
    • SPECIAL FEATURES (Kuesel2000); (Rainey2011aBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; propionate (minor); butyrate (minor); lactate (minor); valerate (minor); isobutyrate (minor); succinate (minor); isovalerate (minor); Hâ‚‚S; ammonia; Hâ‚‚;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Sulfate:
  • not reduced
  • ✗
  • Thiosulfate:
  • not reduced
  • NOTES

    Produces skatol.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (undersized infants - Rainey2011aBergey)
    DNA G+C(%):  27
    Opt. T:  30-37℃
    Lower T(℃):  25(+)
    High T(℃):  45(neg)
    NaCl >6%:  6.5(neg)
    Opt. pH:  6.3
    pH >8:  8.5(neg)
    Bile reaction(%):  20(neg)
    		Aesculin:  vr Starch:  neg Hippurate:  d Milk:  neg Meat:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  + Mannose:  w(+) Rhamnose:  d Ribose:  neg Xylose:  d Cellubiose:  + Lactose:  neg Maltose:  neg Melezitose:  neg Raffinose:  neg Sucrose:  neg Trehalose:  neg Amygdalin:  neg Ethanol:  + Gluconate:  + Glycerol:  + Glycogen:  neg Inulin:  neg Methanol:  neg Pectin:  + Propanol:  + Salicin:  neg Sorbitol:  neg Starch:  neg Arg:  + Ile:  + Leu:  + Ser:  + Val:  + Acetate:  neg Butyrate:  neg Citrate:  neg Formate:  + Fumarate:  neg Lactate:  + Pyruvate:  + Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + Propionate:  minor(+) Butyrate:  minor(+) Lactate:  minor(+) Valerate:  minor(+) Isobutyrate:  minor(+) Succinate:  minor(+) Isovalerate:  minor(+) H2S:  + Ammonia:  + H2:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM SCATOLOGENES
  • Kuesel2000 - Clostridium scatologenes strain SL1 isolated as an acetogenic bacterium from acidic sediments.
  • Rainey2011aBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Clostridiaceae, Genus I. Clostridium - Cluster I
  • ...............................
    • GENERAL REFERENCES FOR CLOSTRIDIUM SCATOLOGENES
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 22, 2021