Clostridium thermarum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium thermarum is a Gram-positive, spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 36.3-36.6%. Clostridium thermarum is likely to be transient and not a long-term gut coloniser. (Liu2020b)



  • This organism has been recovered from hot springs, China. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Liu2020b);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; starch; cellulose;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 1% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-8.0; Grows optimally at pH 7.0.
  • 🌡
  • Temperature tolerance:
  • grows at 28℃; grows at 50℃; Grows optimally at 45℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; glucose; xylose; xylan; cellubiose; glycerol; inositol; mannitol;
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; glucose; inositol; maltose; mannitol; mannose; rhamnose; trehalose; xylose; alanine; arginine; cysteine; lysine; methionine; phenylalanine; proline; serine; threonine; tryptophan; tyrosine; valine;
  • ±
  • Strain-dependent substrate utilisation:
  • arabinose;
  • ±
  • Strain-dependent active enzymes:
  • N-Ac β-glucosaminidase; α-galactosidase; α-glucosidase; Leu arylamidase; Phe arylamidase; pyroGlu arylamidase; Ser arylamidase;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; ethanol;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  hot springs, China
    DNA G+C(%):  36.3-36.6
    Opt. T:  45℃
    Lower T(℃):  28(+)
    High T(℃):  50(+)
    NaCl 0.5-2%:  1(+)
    Opt. pH:  7.0
    pH 6.0-8.0:  6.0-8.0(+)
    		Aesculin:  + Gelatin:  d Starch:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  + Glucose:  + Ribose:  neg Xylose:  + Cellubiose:  + Xylan:  + Glycerol:  + Inositol:  + Mannitol:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  d L-Arabinose:  + Glucose:  + Mannose:  + Rhamnose:  + Xylose:  + Maltose:  + Trehalose:  + Inositol:  + Mannitol:  + Ala:  + Arg:  + Cys:  + Lys:  + Met:  + Phe:  + Pro:  + Ser:  + Thr:  + Trp:  + Tyr:  + Val:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Ac-β-glcamnd:  d α-Galactosidase:  d α-Glucosidase:  d ArgDH:  neg LeuAA:  d PheAA:  d PyrogluAA:  d SerAA:  d

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM THERMARUM
  • Liu2020b - Isolation of Clostridium from Yunnan-Tibet hot springs and description of Clostridium thermarum sp. nov. with lignocellulosic ethanol production
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM THERMARUM
  • New2022 - Collective effects of human genomic variation on microbiome function.
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    • Added: March 18, 2022