Clostridium thermobutyricum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Clostridium thermobutyricum is a Gram-variable, spore-forming, anaerobic, motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 37%. Clostridium thermobutyricum is probably a rare gut coloniser.



  • This organism has been recovered from horse manure compost containing straw and wood shavings. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 5.8; tolerates pH 9.0; Grows optimally at pH 6.8-7.1.
  • 🌡
  • Temperature tolerance:
  • grows at 26℃; grows at 62℃; Grows optimally at 55℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; ribose; xylose; cellubiose; maltose; pyruvate;
  • ⥅
  • Substrates assimilated or utilised:
  • D-glucuronate; D-galacturonate;
  • Active enzymes:
  • Arg arylamidase; α-glucosidase;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (minor); propionate; butyrate; lactate (minor); valerate (trace); CO₂; H₂;
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Clostridiaceae Genus:  Clostridium Gram stain:  vr O2 Relation.:  anaerobic Spore:  Endospore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  horse manure compost containing straw and wood shavings
    DNA G+C(%):  37
    Opt. T:  55℃
    Lower T(℃):  26(+)
    High T(℃):  62(+)
    Opt. pH:  6.8-7.1
    pH 4.2-5.9:  5.8(+)
    pH >8:  9.0(+)
    		Gelatin:  w Casein:  neg Arginine:  neg Meat:  neg Pectin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  + Mannose:  neg Ribose:  + Xylose:  + Cellubiose:  + Maltose:  + Sucrose:  neg Starch:  neg Xylitol:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Ethanol:  neg Methanol:  neg Ile:  neg Leu:  neg Phe:  neg Thr:  neg Val:  neg Fumarate:  neg Malate:  neg Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  neg AlanineAA:  neg ArgAA:  + GlyAA:  neg HisAA:  neg LeuAA:  neg ProAA:  neg PheAA:  neg PyrogluAA:  neg TyrAA:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  minor(+) Propionate:  + Butyrate:  + Lactate:  minor(+) Valerate:  trace(+) CO2:  + H2:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR CLOSTRIDIUM THERMOBUTYRICUM
  • Wiegel1989 - Clostridium thermobutyricum sp. nov., a Moderate Thermophile Isolated from a Cellulolytic Culture, That Produces Butyrate as the Major Product.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CLOSTRIDIUM THERMOBUTYRICUM
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
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    • Added: May 15, 2022