Collinsella bouchesdurhonensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Collinsella bouchesdurhonensis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 57.9%. Collinsella bouchesdurhonensis is probably a common, although minor, coloniser of the gut. (Bilen2017; Bilen2018a)



  • This organism has been recovered from human faeces (CCUG). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 26% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Bilen2018a);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 0.5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-8.0; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 42℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; sorbose; D-tagatose; xylose; cellubiose; gentiobiose; lactose; maltose; melezitose; raffinose; sucrose; trehalose; D-turanose; D-arabitol; mannitol; sorbitol; gluconate; α-methyl glucoside; salicin;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; chymotrypsin; esterase C4; esterase lipase C8; fucosidase; Leu arylamidase; Val arylamidase;
    • SPECIAL FEATURES (Bilen2018a);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Bilen2018a);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; benzylpenicillin; imipenem;
  • Cephalosporins:
  • cefotaxime;
  • Tetracyclines:
  • tigecycline;
  • minocycline;
  • Aminoglycosides:
  • amikacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • daptomycin; colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Coriobacteriales Family:  Coriobacteriaceae Genus:  Collinsella Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (CCUG)
    DNA G+C(%):  57.9
    Opt. T:  37℃
    High T(℃):  42(+)
    NaCl 0.5-2%:  0.5(+)
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  8.5(+)
    		Gelatin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  + D-Tagatose:  + Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  + Melibiose:  neg Sucrose:  + Trehalose:  + Turanose:  + Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  + L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  vr Inositol:  neg Mannitol:  + Sorbitol:  + Xylitol:  neg Gluconate:  + 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  + Me-α-D-Mann:  neg Me-Xyloside:  neg Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  + α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  + Trypsin:  neg CystineAA:  neg LeuAA:  + ValAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(0.64)
    benzyl-pen:  S(0.006)
    imipenem:  S(0.12)
    cefotaxime:  S(0.125)
    amikacin:  R(>256)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  R(4)
    tigecycline:  S(0.19)
    teicoplanin:  S(0.016)
    vancomycin:  S(1)
    rifampicin:  S(0.004)
    metronidazole:  S(0.064)
    daptomycin:  R(2)
    colistin:  R(>256)

    References

    SPECIFIC REFERENCES FOR COLLINSELLA BOUCHESDURHONENSIS
  • Bilen2017 - Collinsella bouchesdurhonensis' sp. nov., identified in human stool sample.
  • Bilen2018a - Genomic and phenotypic description of the newly isolated human species Collinsella bouchesdurhonensis sp. nov.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR COLLINSELLA BOUCHESDURHONENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • ...............................
    • GENERAL REFERENCES FOR COLLINSELLA BOUCHESDURHONENSIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: July 12, 2021