Comamonas kerstersii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Comamonas kerstersii is a Gram-negative, non-spore-forming, aerobic, motile, rod-shaped bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 59.7-63.3%. Comamonas kerstersii is probably a rare gut coloniser. (Wauters2003)



  • This organism has been recovered from human faeces and clinical sources (blood, appendix - CCUG). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Wauters2003);
    Character Response
  • Substrates hydrolysed or digested:
  • tyrosine;
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 44℃; Grows optimally at 35-40℃.
  • ⥅
  • Substrates assimilated or utilised:
  • proline; acetate; 3-hydroxybutyrate; 4-hydroxybenzoate; itaconate; lactate; suberate; valerate;
  • ±
  • Strain-dependent substrate utilisation:
  • caprate;
  • Active enzymes:
  • catalase; esterase lipase C8; Leu arylamidase; oxidase;
    • SPECIAL FEATURES (Wauters2003);
    Character Response
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✓
  • Nitrate:
  • reduced
  • ✗
  • Nitrite:
  • not reduced
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Miscellaneous antibiotics:
  • colistin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Burkholderiales Family:  Comamonadaceae Genus:  Comamonas Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces and clinical sources (blood, appendix - CCUG)
    DNA G+C(%):  59.7-63.3
    Opt. T:  35-40℃
    Lower T(℃):  30(+)
    High T(℃):  44(+)
    		Aesculin:  neg Urea:  neg Gelatin:  neg Tyrosine:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Ala:  neg Pro:  + Acetate:  + Caprate:  d 3-Hydroxybutyrate:  + 3-Hydroxybenzoate:  neg 4-Hydroxybenzoate:  + Itaconate:  + Lactate:  + Suberate:  + Valerate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg LysDC:  neg OrnDC:  neg LeuAA:  + PyrrolidAA:  neg AlkalineP:  neg AcidP:  neg Esterase(C4):  vr EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    colistin:  Sens

    References

    SPECIFIC REFERENCES FOR COMAMONAS KERSTERSII
  • Wauters2003 - Description of Comamonas aquatica comb. nov. and Comamonas kerstersii sp. nov. for two subgroups of Comamonas terrigena and emended description of Comamonas terrigena.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR COMAMONAS KERSTERSII
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • ...............................
    • GENERAL REFERENCES FOR COMAMONAS KERSTERSII
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021