Conexibacter woesei

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Conexibacter woesei is a Gram-positive, non-spore-forming, aerobic, motile, short rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 71%. Conexibacter woesei is probably a rare gut coloniser. (Monciardini2003)



  • This organism has been recovered from temperate forest soil. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Monciardini2003);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; gelatin;
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7-7.5.
  • 🌡
  • Temperature tolerance:
  • grows at 28℃; grows at 37℃;
  • ⥅
  • Substrates assimilated or utilised:
  • L-arabinose; glycerol; ribose; xylose; acetate; 3-hydroxybutyrate; 2-ketoglutarate; propionate; pyruvate; α-ketovalerate; methyl pyruvate;
  • Active enzymes:
  • acid phosphatase; catalase; esterase C4; esterase lipase C8; Leu arylamidase; oxidase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Monciardini2003);
    Character Response
  • ✓
  • NO3➔NO2:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Monciardini2003);
    Class Active Resistant
  • Penicillins:
  • ampicillin; aztreonam; methicillin; oxacillin;
  • Cephalosporins:
  • ceftazidime;
  • Quinolines:
  • ciprofloxacin; norfloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin;
  • kanamycin; streptomycin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • nitrofurantoin;
  • trimethoprim;
  • Vancomycins:
  • teicoplanin;
  • Miscellaneous antibiotics:
  • novobiocin; polymyxin B;
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Thermoleophilia Order:  Solirubrobacterales Family:  Conexibacteraceae Genus:  Conexibacter Gram stain:  + O2 Relation.:  aerobic Spore:  No spore Motility:  Swimming Morphology:  Short Rod
    Health:  Unknown
    Source:  temperate forest soil
    DNA G+C(%):  71
    Lower T(℃):  28(+)
    Mid T(℃):  37(+)
    Opt. pH:  7-7.5
    		Aesculin:  + Urea:  neg Gelatin:  + Tween:  40(neg) 80(neg)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  + Fructose:  neg Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Ribose:  + D-Tagatose:  neg Xylose:  + Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Maltotriose:  neg Melezitose:  neg Melibiose:  neg Raffinose:  neg Sucrose:  neg D-Turanose:  neg Trehalose:  neg N_Acetyl_glucosamine:  neg Adonitol:  neg Amygdalin:  neg D-Arabitol:  neg Arbutin:  neg Dextrin:  neg Erythritol:  neg Gluconate:  neg Glucosamine:  neg Glycerol:  + Glycogen:  neg Inositol:  neg Inulin:  neg Mannitol:  neg Me-α-D-Glc:  neg Salicin:  neg Sorbitol:  neg Xylitol:  neg Ala:  neg D-Ala:  neg 4-Aminobutyrate:  neg Asp:  neg Glu:  neg His:  neg Leu:  neg Orn:  neg Phe:  neg Pro:  neg Ser:  neg Thr:  neg Acetate:  + Aconitate:  cis(neg) Adipate:  neg Caprate:  neg Citrate:  neg Formate:  neg 3-Hydroxybutyrate:  + Itaconate:  neg Lactate:  neg DL-Lactate:  neg L-Malate:  neg Malonate:  neg Phenylacetate:  neg Propionate:  + Pyruvate:  + Quinate:  neg Saccharate:  neg Sebacate:  neg Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg CystineAA:  neg LeuAA:  + ValAA:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  R(10; disc)
    aztreonam:  R(100; disc)
    methicillin:  R(5; disc)
    oxacillin:  R(1; disc)
    ceftazidime:  R(30; disc)
    amikacin:  S(30; disc)
    gentamicin:  S(10; disc)
    kanamycin:  R(30; disc)
    streptomycin:  R(10; disc)
    tobramycin:  R(10; disc)
    erythromycin:  Var(MIC50): 15; disc), MIC90: Var(15; disc
    ciprofloxacin:  R(5; disc)
    norfloxacin:  R(10; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Var(MIC50): 30; disc), MIC90: Var(30; disc
    teicoplanin:  S(30; disc)
    vancomycin:  Var(MIC50): 30; disc), MIC90: Var(30; disc
    rifampicin:  R(30; disc)
    chloramphenicol:  Var(MIC50): 30; disc), MIC90: Var(30; disc
    nitrofurantoin:  S(300; disc)
    trimethoprim:  R(5; disc)
    clindamycin:  R(2; disc)
    novobiocin:  S(30; disc)
    polymyxin_B:  S(300U)

    References

    SPECIFIC REFERENCES FOR CONEXIBACTER WOESEI
  • Monciardini2003 - Conexibacter woesei gen. nov., sp. nov., a novel representative of a deep evolutionary line of descent within the class Actinobacteria.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CONEXIBACTER WOESEI
  • Frank2007 - Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: March 18, 2022