Coprococcus catus

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Coprococcus catus is a Gram-positive, strictly anaerobic, non-motile, coccus bacterium. It has been detected in at least 24 gut microbiome compilation studies or metastudies. The DNA G+C content is 41%. Coprococcus catus is often a widespread coloniser of gut. (Holdeman1974; Ezaki2011dBergey)



  • This organism has been recovered from human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Holdeman1974); (Ezaki2011dBergey);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 6.5% salt;
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 30℃; grows at 37℃; grows at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; mannitol;
  • ⥅
  • Substrates assimilated or utilised:
  • glucose; mannitol; acetate; lactate; DL-lactate; L-lactate;
    • SPECIAL FEATURES (Holdeman1974); (Ezaki2011dBergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (minor); propionate; butyrate;
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; ammonia;
  • Haemolysis:
  • alpha (weak)
  • NOTES

    This is an inhabitant of the human gut.

    Fuel sources used:
    It can use fibre, simple sugars (including lactose) and protein for energy.

    Metabolites produced:
    Our genomic analysis indicates that most members of this species can produce the following metabolites: acetate, BCAAs, butyrate, lactate, propionate, succinate, cobalamin, folate, biotin, riboflavin.

    Metabolites consumed:
    In addition, our genomic analysis indicates that most members of this species can consume the following metabolites: oxalate.

  • N/A

  • C. catus has been reported to produce butyrate and propionate. [PMID: 24553467] Coprococcus catus has been reported to take the acrylate pathway for propionate production, in which lactate is consumed. [https://doi.org/10.3389/fmicb.2019.0120] Coprococcus is an anerobic genus. [doi:10.1099/00207713-24-2-260]

  • GutFeeling KnowledgeBase COMMENTS [Website]

    Coprococcus is an anerobic genus. [doi:10.1099/00207713-24-2-260]

  • Holdeman, L. V., & Moore, W. E. C. (1974). New genus, Coprococcus, twelve new species, and emended descriptions of four previously described species of bacteria from human feces. International Journal of Systematic Bacteriology, 24(2), 260–277.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Lachnospiraceae Genus:  Coprococcus Gram stain:  + O2 Relation.:  strictly anaerobic Motility:  Sessile Morphology:  Coccus
    Health:   Positive
    Source:  human faeces
    DNA G+C(%):  41
    Lower T(℃):  30(neg)
    Mid T(℃):  37(+)
    High T(℃):  45(+)
    NaCl >6%:  6.5(neg)
    Bile reaction(%):  20(+)
    		Aesculin:  neg Starch:  neg Hippurate:  neg Milk:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Glucose:  w Mannose:  neg Ribose:  neg Sorbose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  w(neg) Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Amygdalin:  neg Aesculin:  neg Inulin:  neg Starch:  neg Adonitol:  neg Dulcitol:  neg Glycerol:  neg Mannitol:  d(+) Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Glucose:  w(+) Mannose:  neg Sorbose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Raffinose:  neg Sucrose:  neg Adonitol:  neg Dextrin:  neg Dulcitol:  neg Glycerol:  neg Inulin:  neg Mannitol:  + Acetate:  + Lactate:  + DL-Lactate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  minor(+) Propionate:  + Butyrate:  + H2S:  neg Ammonia:  neg

    References

    SPECIFIC REFERENCES FOR COPROCOCCUS CATUS
  • Holdeman1974 - New Genus, Coprococcus, Twelve New Species, and Emended Descriptions of Four Previously Described Species of Bacteria from Human Feces.
  • Ezaki2011dBergey - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Lachnospiraceae, Genus VII. Coprococcus
  • Salyers1977 - Fermentation of mucins and plant polysaccharides by anaerobic bacteria from the human colon
  • Gao2020 - Functional Microbiomics Reveals Alterations of the Gut Microbiome and Host Co-Metabolism in Patients With Alcoholic Hepatitis
  • Bajer2017 - Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis
  • Huang2019 - Analysis of microbiota in elderly patients with Acute Cerebral Infarction
  • Jackson2016 - Signatures of early frailty in the gut microbiota
  • Liu2016a - Remodeling of the gut microbiota and structural shifts in Preeclampsia patients in South China
  • Wang2019b - Alterations in the human gut microbiome associated with Helicobacter pylori infection
  • Luna2016 - Distinct Microbiome-Neuroimmune Signatures Correlate With Functional Abdominal Pain in Children With Autism Spectrum Disorder.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR COPROCOCCUS CATUS
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Chung2019 - Impact of carbohydrate substrate complexity on the diversity of the human colonic microbiota.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Karlsson2013 - Gut metagenome in European women with normal, impaired and diabetic glucose control
  • King2019 - Baseline human gut microbiota profile in healthy people and standard reporting template.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • LeChatelier2013 - Richness of human gut microbiome correlates with metabolic markers
  • Moore1974 - Human fecal flora: the normal flora of 20 Japanese-Hawaiians.
  • PerezBrocal2015 - Metagenomic Analysis of Crohn's Disease Patients Identifies Changes in the Virome and Microbiome Related to Disease Status and Therapy, and Detects Potential Interactions and Biomarkers
  • PerisBondia2011 - The active human gut microbiota differs from the total microbiota.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
  • Wang2018 - A metagenome-wide association study of gut microbiota in asthma in UK adults
  • Wang2018a - Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • Zupancic2012 - Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome.
  • ...............................
    • GENERAL REFERENCES FOR COPROCOCCUS CATUS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: February 08, 2021