Corynebacterium appendicis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Corynebacterium appendicis is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 65.8%. Corynebacterium appendicis is probably a rare gut coloniser. (Yassin2002a; Bernard2012Bergey)



  • This organism has been recovered from an appendix and human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). It is an opportunistic pathogen. Is a known gut commensal.
    • QUIRKS
  • Lipophilic.
    • GENERAL CHARACTERISTICS (Yassin2002a); (Bernard2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • urea;
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; maltose; pullulan; glycerol;
  • Active enzymes:
  • alkaline phosphatase; catalase; urease;
    • SPECIAL FEATURES (Yassin2002a);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate (major);
  • ✗
  • Metabolites not produced:
  • propionate; indole;
  • ✓
  • VP test:
  • active
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
  • NOTES

    TSBA, tuberculostearic acid positive

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Corynebacteriaceae Genus:  Corynebacterium Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  an appendix and human faeces
    DNA G+C(%):  65.8
    		Aesculin:  neg Urea:  + Gelatin:  neg Starch:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Glucose:  d(+) Rhamnose:  neg Ribose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  d(+) Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Glycogen:  neg Inulin:  neg D-Arabitol:  neg L-Arabitol:  neg Glycerol:  + Mannitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  + Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg AlaPheProAA:  neg CystineAA:  neg LeuAA:  neg PyrrolidAA:  neg PyrogluAA:  neg ValAA:  neg AlkalineP:  + AcidP:  neg Esterase(C4):  neg EstLip(C8):  neg Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Propionate:  neg Lactate:  Major(+) Indole:  neg

    References

    SPECIFIC REFERENCES FOR CORYNEBACTERIUM APPENDICIS
  • Yassin2002a - Corynebacterium appendicis sp. nov.
  • Bernard2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Corynebacteriaceae, Genus I. Corynebacterium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CORYNEBACTERIUM APPENDICIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
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    • Added: April 08, 2021