Corynebacterium cystitidis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Corynebacterium cystitidis is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 52.6-53.9%. Corynebacterium cystitidis is probably a rare gut coloniser. (Yanagawa1978; Bernard2012Bergey)



  • This organism has been recovered from bovine sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: animal pathogen). It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Yanagawa1978); (Bernard2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • hippurate; starch; urea;
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 5.4; tolerates pH 9.0;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 5℃; grows at 41.5℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; xylose; starch; maltose; trehalose;
  • Active enzymes:
  • catalase; urease;
    • SPECIAL FEATURES (Yanagawa1978);
    Character Response
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✗
  • Methyl red test:
  • not active
  • ✗
  • VP test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Yanagawa1978);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Macrolides:
  • erythromycin; oleandomycin;
  • Tetracyclines:
  • chlortetracycline; tetracycline;
  • Quinolines:
  • nalidixic-acid;
  • Aminoglycosides:
  • kanamycin; neomycin;
  • streptomycin;
  • Polypep/ketides:
  • bacitracin;
  • Miscellaneous antibiotics:
  • polymyxin B;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Corynebacteriaceae Genus:  Corynebacterium Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  bovine sources
    DNA G+C(%):  52.6-53.9
    Low T(℃):  5(neg)
    High T(℃):  41.5(+)
    pH 4.2-5.9:  5.4(neg)
    pH >8:  9.0(+)
    		Aesculin:  neg Urea:  + Gelatin:  neg Starch:  + Casein:  neg Arginine:  neg DNA:  neg Tyrosine:  neg Hippurate:  + Tween:  80(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  + Galactose:  neg Glucose:  + Mannose:  neg Rhamnose:  neg Xylose:  + Lactose:  neg Maltose:  + Sucrose:  neg Trehalose:  + Starch:  + Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Malonate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  + ArgDC:  neg LysDC:  neg OrnDC:  neg Phe deaminase:  neg DNAse:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  R(1U)
    kanamycin:  S(10)
    neomycin:  S(2)
    streptomycin:  R(2.5)
    erythromycin:  S(0.02)
    oleandomycin:  S(0.2)
    nalidixic-acid:  R(100)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    chlortetracycline:  R(100)
    tetracycline:  R(1)
    bacitracin:  S(1)
    polymyxin_B:  R(500U)

    References

    SPECIFIC REFERENCES FOR CORYNEBACTERIUM CYSTITIDIS
  • Yanagawa1978 - Corynebacterium pilosum and Corynebacterium cystitidis, Two New Species from Cows
  • Bernard2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Corynebacteriaceae, Genus I. Corynebacterium
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CORYNEBACTERIUM CYSTITIDIS
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
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    • Added: January 19, 2022