Corynebacterium diphtheriae

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Corynebacterium diphtheriae is a Gram-variable, non-spore-forming, anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 52-55%. Corynebacterium diphtheriae is unlikely to be a gut coloniser. (Riegel1995a; Bernard2012Bergey)



  • This organism has been recovered from clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: toxin produced; vaccine available). Is a known human pathogen. Likely to be transient and not a long-term gut commensal.
    • GENERAL CHARACTERISTICS (Riegel1995a); (Bernard2012Bergey);
    Character Response
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 30-37℃.
  • ±
  • Strain-dependent acid from carbs:
  • sucrose;
  • Active enzymes:
  • catalase;
    • SPECIAL FEATURES (Riegel1995a);
    Character Response
  • ✓
  • Metabolites produced:
  • propionate;
  • ±
  • Nitrate:
  • reduced by most strains

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Corynebacteriaceae Genus:  Corynebacterium Gram stain:  vr O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  clinical sources
    DNA G+C(%):  52-55
    Opt. T:  30-37℃
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Sucrose:  d
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  +

    References

    SPECIFIC REFERENCES FOR CORYNEBACTERIUM DIPHTHERIAE
  • Nouioui2018 - Genome-Based Taxonomic Classification of the Phylum Actinobacteria.
  • Riegel1995a - Taxonomy of Corynebacterium diphtheriae and related taxa, with recognition of Corynebacterium ulcerans sp. nov. nom. rev.
  • Bernard2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Corynebacteriaceae, Genus I. Corynebacterium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CORYNEBACTERIUM DIPHTHERIAE
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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    • Added: January 14, 2022