Corynebacterium falsenii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Corynebacterium falsenii is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, club-shaped-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Corynebacterium falsenii is probably a rare gut coloniser. (Sjoden1998; Bernard2012Bergey)



  • This organism has been recovered from clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • QUIRKS
  • Nonlipophilic.
    • GENERAL CHARACTERISTICS (Sjoden1998); (Bernard2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • urea;
  • H+
  • Acid from carbohydrates usually produced:
  • galactose; glucose; ribose; trehalose; glycerol; 5-ketogluconate;
  • ±
  • Strain-dependent acid from carbs:
  • fructose; rhamnose; D-tagatose; lactose; maltose;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; catalase; esterase C4; esterase lipase C8; phosphoamidase; urease;
  • ±
  • Strain-dependent active enzymes:
  • cystine arylamidase; Leu arylamidase; lipase C14;
    • SPECIAL FEATURES (Sjoden1998);
    Character Response
  • ✗
  • Nitrate:
  • not reduced
  • Pigments:
  • yellow
    • RESPONSE TO ANTIBIOTICS (Sjoden1998);
    Class Active Resistant
  • Penicillins:
  • imipenem; penicillin;
  • aztreonam;
  • Cephalosporins:
  • cephalothin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol; fusidic-acid;
  • fosfomycin;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Corynebacteriaceae Genus:  Corynebacterium Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Club rod Pigment:  yellow
    Health:  Unknown
    Source:  clinical sources
    		Aesculin:  neg Urea:  + Casein:  neg Tyrosine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  d D-Fucose:  neg Galactose:  + Glucose:  + D-Lyxose:  neg Rhamnose:  d Ribose:  + Sorbose:  neg D-Tagatose:  d Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  d Maltose:  d Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  + Turanose:  neg Amygdalin:  neg Glycogen:  neg Adonitol:  neg D-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  + Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  + Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  + Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Glucosidase:  neg α-Mannosidase:  neg Chymotrypsin:  neg Trypsin:  neg CystineAA:  d LeuAA:  d PyrrolidAA:  neg ValAA:  neg AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  d Phosphoamidase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  yellow
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    aztreonam:  R(>64)
    oxacillin:  RNG: (4-8)
    penicillin:  SensRNG: 90.25-0.5)
    imipenem:  SensRNG: (0.0625-0.125)
    cephalothin:  SensRNG: (0.5-1)
    gentamicin:  SensRNG: (0.5-1
    erythromycin:  SensRNG: (<0.03-0.0625)
    ciprofloxacin:  S(0.5)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(1)
    vancomycin:  SensRNG: (1-2)
    rifampicin:  S(0.016)
    chloramphenicol:  SensRNG: (1-2)
    fosfomycin:  R(>256)
    fusidic-acid:  S(0.03)

    References

    SPECIFIC REFERENCES FOR CORYNEBACTERIUM FALSENII
  • Sjoden1998 - Description of some coryneform bacteria isolated from human clinical specimens as Corynebacterium falsenii sp. nov.
  • Bernard2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Corynebacteriaceae, Genus I. Corynebacterium
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CORYNEBACTERIUM FALSENII
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
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    • Added: January 19, 2022