Corynebacterium genitalium

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Corynebacterium genitalium is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, short rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 62.8%. Corynebacterium genitalium is probably a rare gut coloniser.



  • This organism has been recovered from industrial sources and clinical specimens. Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • GENERAL CHARACTERISTICS
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 7.5% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 36℃;
  • Active enzymes:
  • alkaline phosphatase; catalase; esterase lipase C8;
  • ±
  • Strain-dependent active enzymes:
  • acid phosphatase; esterase C4; Leu arylamidase; naphthol-ASBI-P;
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • ciprofloxacin; moxifloxacin;
  • Polypep/ketides:
  • rifampicin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin; linezolid;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Corynebacteriaceae Genus:  Corynebacterium Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Short Rod
    Health:  Unknown
    Source:  industrial sources and clinical specimens
    DNA G+C(%):  62.8
    Mid T(℃):  36(+)
    NaCl >6%:  7.5(+)
    		Gelatin:  neg Starch:  neg Hippurate:  neg Tween:  80(d)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  neg Glucose:  neg Ribose:  neg Maltose:  neg Sucrose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  vr α-Glucosidase:  neg β-Glucuronidase:  neg LeuAA:  d PyrrolidAA:  neg AlkalineP:  + AcidP:  d Esterase(C4):  d EstLip(C8):  + Lipase(C14):  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  S(1U)
    linezolid:  S(10)
    ciprofloxacin:  S(5)
    moxifloxacin:  S(5)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(30)
    vancomycin:  S(5)
    rifampicin:  S(5)
    clindamycin:  S(2)

    References

    SPECIFIC REFERENCES FOR CORYNEBACTERIUM GENITALIUM
  • Furness1976 - Infection of a nonspecific urethritis patient and his consort with a pathogenic species of nonspecific urethritis Corynebacteria, Corynebacterium genitalium, N. SP.
  • JaenLuchoro2022 - Corynebacterium genitalium sp. nov., nom. rev. and Corynebacterium pseudogenitalium sp. nov., nom. rev., two old species of the genus Corynebacterium described from clinical and environmental samples.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CORYNEBACTERIUM GENITALIUM
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: October 10, 2022