Corynebacterium stationis

(aka Brevibacterium stationis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Corynebacterium stationis, (aka Brevibacterium stationis), is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 53.9%. Corynebacterium stationis is probably a rare gut coloniser. (Bernard2010; Bernard2012Bergey)



  • This organism has been recovered from human faeces (infant stools - Bernard2010), clinical sources (blood) and seawater. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Is a rare opportunistic pathogen. A possible gut commensal.
    • QUIRKS
  • Nonlipophilic.
    • GENERAL CHARACTERISTICS (Bernard2010); (Bernard2012Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • tyrosine; urea;
  • 🧂
  • Salt tolerance:
  • tolerates 10% salt;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 42℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; ribose;
  • Active enzymes:
  • catalase; urease;
  • ±
  • Strain-dependent active enzymes:
  • esterase; Leu arylamidase;
    • SPECIAL FEATURES (Bernard2010);
    Character Response
  • ✗
  • Metabolites not produced:
  • propionate; indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • ✓
  • Nitrate:
  • reduced
  • ✗
  • Nitrite:
  • not reduced
  • ✓
  • NO3➔NO2:
  • reduced
  • Pigments:
  • yellow
    • RESPONSE TO ANTIBIOTICS (Bernard2010);
    Class Active Resistant
  • Penicillins:
  • ampicillin; ertapenem; meropenem; penicillin;
  • Cephalosporins:
  • cefepime; cefotaxime; cefuroxime;
  • Macrolides:
  • erythromycin; quinupristin-dalfopristin; telithromycin;
  • Tetracyclines:
  • tetracycline; tigecycline;
  • Quinolines:
  • ciprofloxacin; gatifloxacin; levofloxacin; moxifloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin; daptomycin; linezolid; telithromycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Corynebacteriales Family:  Corynebacteriaceae Genus:  Corynebacterium Alt. name:  Brevibacterium stationis Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  yellow
    Health:  Unknown
    Source:  human faeces (infant stools - Bernard2010), clinical sources (blood) and seawater
    DNA G+C(%):  53.9
    Lower T(℃):  25(+)
    High T(℃):  42(+)
    NaCl >6%:  10(+)
    		Aesculin:  neg Urea:  + Gelatin:  neg Starch:  neg Casein:  neg DNA:  neg Tyrosine:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  + Fucose:  w Galactose:  neg Glucose:  + Mannose:  + Ribose:  + Xylose:  neg Lactose:  neg Maltose:  neg Trehalose:  neg Aesculin:  neg Glycogen:  neg Glycerol:  neg Mannitol:  neg Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  + Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDC:  neg Chymotrypsin:  neg LysDC:  neg OrnDC:  neg Trypsin:  neg CystineAA:  neg LeuAA:  d PyrrolidAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  neg DNAse:  neg Esterase:  d EstLip(C8):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Propionate:  neg Indole:  neg Pigment:  yellow
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Sens
    penicillin:  Sens
    ertapenem:  Sens
    meropenem:  Sens
    cefepime:  Sens
    cefotaxime:  Sens
    cefuroxime:  Sens
    gentamicin:  Sens
    erythromycin:  Sens
    quin-dalf:  Sens
    telithromycin:  Sens
    linezolid:  Sens
    ciprofloxacin:  Sens
    gatifloxacin:  Sens
    levofloxacin:  Sens
    moxifloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Sens
    tigecycline:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    chloramphenicol:  Sens
    SXT:  Sens
    clindamycin:  Sens
    daptomycin:  Sens

    References

    SPECIFIC REFERENCES FOR CORYNEBACTERIUM STATIONIS
  • Bernard2010 - Assignment of Brevibacterium stationis (ZoBell and Upham 1944) Breed 1953 to the genus Corynebacterium, as Corynebacterium stationis comb. nov., and emended description of the genus Corynebacterium to include isolates that can alkalinize citrate.
  • Bernard2012Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Corynebacteriaceae, Genus I. Corynebacterium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR CORYNEBACTERIUM STATIONIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: July 12, 2021