Dakarella massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Dakarella massiliensis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 57%. Dakarella massiliensis is probably a rare gut coloniser. (Dione2017)



  • This organism has been recovered from vaginal flora. Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Dione2017);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • galactose; glucose; D-tagatose; aesculin; glycogen; starch; cellubiose; lactose; maltose; raffinose; sucrose; trehalose; D-turanose; glycerol; salicin;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; Arg arylamidase; chymotrypsin; esterase C4; esterase lipase C8; α-galactosidase; β-glucosidase; Leu arylamidase; lipase C14; α-mannosidase; phosphoamidase; trypsin; Val arylamidase;
    • SPECIAL FEATURES (Dione2017);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Dione2017);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem; penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Betaproteobacteria Order:  Burkholderiales Family:  Sutterellaceae Genus:  Dakarella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  vaginal flora
    DNA G+C(%):  57
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Galactose:  + Glucose:  + D-Tagatose:  + Cellubiose:  + Lactose:  + Maltose:  + Sucrose:  + Trehalose:  + Turanose:  + Aesculin:  + Glycogen:  + Starch:  + Glycerol:  + Mannitol:  neg Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg α-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  + α-Mannosidase:  + Chymotrypsin:  + Trypsin:  + ArgAA:  + LeuAA:  + ValAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  + Phosphoamidase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    penicillin:  Sens
    imipenem:  Sens
    gentamicin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    vancomycin:  Res
    rifampicin:  Sens
    metronidazole:  Sens
    SXT:  Res
    clindamycin:  Sens

    References

    SPECIFIC REFERENCES FOR DAKARELLA MASSILIENSIS
  • Dione2017 - Dakarella massiliensis gen. nov., sp. nov., strain ND3T: a new bacterial genus isolated from the female genital tract.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR DAKARELLA MASSILIENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • ...............................
    • Added: January 14, 2022