Dehalobacter restrictus

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Dehalobacter restrictus is a Gram-negative, non-spore-forming, strictly anaerobic, motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 45.3%. Dehalobacter restrictus is unlikely to be a gut coloniser. (Holliger1998)



  • This organism has been recovered from sediment of the Rhine River. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Dechlorinates tetra- and trichlorethane. Non-fermentative. Unlikely gut coloniser.
    • GENERAL CHARACTERISTICS (Holliger1998);
    Character Response
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 8.0; Grows optimally at pH 6.8-7.6.
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 35℃; Grows optimally at 25-30℃.
  • ⥅
  • Substrates assimilated or utilised:
  • arginine; histidine; threonine; acetate; H2 consumed;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Nitrite:
  • not reduced
  • ✗
  • Thiosulfate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Peptococcaceae Genus:  Dehalobacter Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  sediment of the Rhine River
    DNA G+C(%):  45.3
    Opt. T:  25-30℃
    Lower T(℃):  25(+)
    Mid T(℃):  35(+)
    Opt. pH:  6.8-7.6
    pH 6.0-8.0:  8.0(neg)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Fructose:  neg Glucose:  neg Xylose:  neg Ethanol:  neg Glycerol:  neg Methanol:  neg Propanol:  neg Ala:  neg Arg:  + Asp:  neg Glu:  neg Gly:  neg His:  + Thr:  + Acetate:  + Butyrate:  neg Formate:  neg Fumarate:  neg Lactate:  neg Propionate:  neg Pyruvate:  neg Succinate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg

    References

    SPECIFIC REFERENCES FOR DEHALOBACTER RESTRICTUS
  • Holliger1998 - Dehalobacter restrictus gen. nov. and sp. nov., a strictly anaerobic bacterium that reductively dechlorinates tetra- and trichloroethene in an anaerobic respiration.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR DEHALOBACTER RESTRICTUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
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    • Added: March 18, 2022