Dermacoccus nishinomiyaensis

(aka Micrococcus nishinomiyaensis)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Dermacoccus nishinomiyaensis, (aka Micrococcus nishinomiyaensis), is a Gram-positive, non-spore-forming, aerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. Dermacoccus nishinomiyaensis is probably a rare gut coloniser. (PathomAree2006; Stackebrandt1995)



  • This organism has been recovered from human skin, clinical sources (blood - CCUG) and human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Is a rare opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (PathomAree2006); (Stackebrandt1995);
    Character Response
  • Substrates hydrolysed or digested:
  • DNA; gelatin;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 10% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 10℃;
  • ⥅
  • Substrates assimilated or utilised:
  • aspartate; glutamate; lysine; proline; tryptophan; valine; glutamine;
  • ±
  • Strain-dependent substrate utilisation:
  • fructose; mannose;
  • Active enzymes:
  • acid phosphatase; catalase; esterase lipase C8; fucosidase; α-glucosidase; β-glucosidase; Leu arylamidase; lipase C14; oxidase; trypsin; urease;
    • SPECIAL FEATURES (PathomAree2006); (Stackebrandt1995);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
  • Nitrite:
  • reduction is variable
    • RESPONSE TO ANTIBIOTICS (Stackebrandt1995);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • methicillin;
  • Macrolides:
  • erythromycin;
  • Aminoglycosides:
  • neomycin; streptomycin;
  • Heterocycles:
  • chloramphenicol;
  • Miscellaneous antibiotics:
  • novobiocin;

  • Lagier, J.-C., Armougom, F., Million, M., Hugon, P., Pagnier, I., Robert, C., Bittar, F., Fournous, G., Gimenez, G., Maraninchi, M., Trape, J.-F., Koonin, E. V., La Scola, B., & Raoult, D. (2012). Microbial culturomics: paradigm shift in the human gut microbiome study. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 18(12), 1185–1193.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Actinomycetia Order:  Micrococcales Family:  Dermacoccaceae Genus:  Dermacoccus Alt. name:  Micrococcus nishinomiyaensis Gram stain:  + O2 Relation.:  aerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  human skin, clinical sources (blood - CCUG) and human faeces
    Low T(℃):  10(neg)
    NaCl >6%:  10(neg)
    		Aesculin:  neg Urea:  neg Gelatin:  + Starch:  vr DNA:  + Tween:  80(vr)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Glucose:  neg Ribose:  neg Xylose:  neg Lactose:  neg Maltose:  neg Glycogen:  neg Mannitol:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Fructose:  d(neg) Galactose:  neg Glucose:  vr Mannose:  d(neg) Rhamnose:  neg Xylose:  neg Lactose:  neg Sucrose:  neg Glycerol:  neg Mannitol:  neg Asp:  + Glu:  + Lys:  + Pro:  + Trp:  + Val:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  d(+) Coagulase:  neg Ac-β-glcamnd:  neg α-Fucosidase:  + α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg LysDC:  neg OrnDC:  neg Phe deaminase:  neg Trypsin:  + LeuAA:  + PyrrolidAA:  neg AlkalineP:  neg AcidP:  + DNAse:  neg Esterase(C4):  neg EstLip(C8):  + Lecithinase:  neg Lipase(C14):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    methicillin:  R(vr)
    penicillin:  S(vr)
    neomycin:  Sens
    streptomycin:  S(vr)
    erythromycin:  S(vr)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    chloramphenicol:  S(vr)
    novobiocin:  Sens

    References

    SPECIFIC REFERENCES FOR DERMACOCCUS NISHINOMIYAENSIS
  • PathomAree2006 - Dermacoccus barathri sp. nov. and Dermacoccus profundi sp. nov., novel actinomycetes isolated from deep-sea mud of the Mariana Trench.
  • Stackebrandt1995 - Taxonomic Dissection of the Genus Micrococcus: Kocuria gen. nov., Nesterenkonia gen. nov., Kytococcus gen. nov., Dermacoccus gen. nov., and Micrococcus Cohn 1872 gen. emend.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR DERMACOCCUS NISHINOMIYAENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
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    • Added: April 08, 2021