Desulfovibrio piger

(aka Desulfomonas pigra)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Desulfovibrio piger, (aka Desulfomonas pigra), is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 21 gut microbiome compilation studies or metastudies. The DNA G+C content is 64%. Desulfovibrio piger is a common gut coloniser. (Loubinoux2002; Moore1976; Kuever2005Bergey)



  • This organism has been recovered from human faeces. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal.
    • GENERAL CHARACTERISTICS (Loubinoux2002); (Moore1976); (Kuever2005Bergey);
    Character Response
  • 💧
  • Bile tolerance:
  • Resistant to 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 37℃; Grows optimally at 37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • ethanol; lactate; pyruvate;
    • SPECIAL FEATURES (Moore1976); (Kuever2005Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; H₂S;
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrite:
  • not reduced
  • ✓
  • Sulfate:
  • reduced
  • ✓
  • Thiosulfate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Goldstein2006); (Goldstein2000a);
    Class Active Resistant
  • Penicillins:
  • ampicillin-sulbactam; imipenem; ticarcillin-clavulanic acid;
  • Cephalosporins:
  • cefmetazole;
  • Heterocycles:
  • chloramphenicol; metronidazole;
  • NOTES

    Required growth factor: 3-aminobenzoate.  Produces sulfite reductase.

  • Moore, W. E. C., Johnson, J. L., & Holdeman, L. V. (1976). Emendation of Bacteroidaceae and Butyrivibrio and descriptions of Desulfomonas gen. Nov. And ten new species in the genera Desulfomonas, Butyrivibrio, Eubacterium, Clostridium, and Ruminococcus. International Journal of Systematic Bacteriology, 26(2), 238–252.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Deltaproteobacteria Order:  Desulfovibrionales Family:  Desulfovibrionaceae Genus:  Desulfovibrio Alt. name:  Desulfomonas pigra Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  64
    Opt. T:  37℃
    Mid T(℃):  37(+)
    Bile reaction(%):  20(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Ethanol:  + Fumarate:  neg Lactate:  + Malate:  neg Pyruvate:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + H2S:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amp-sulb:  S(MIC50): 0.5, MIC90: 4, RNG: (0.06->32)
    piper-taz:  Var(MIC50): 0.25, MIC90: >128, RNG: (0.06->128)
    tica-clav:  S(MIC50): 0.25, MIC90: 4, RNG: (0.06->128)
    imipenem:  S(MIC50): 0.125, MIC90: 0.5, RNG: (0.015–16)
    cefmetazole:  R(16)
    cefoxitin:  Var(MIC50): 2, MIC90: 32, RNG: (0.25–>128)
    levofloxacin:  Var(MIC50): 0.5, MIC90: >16, RNG: (0.06–>16)
    moxifloxacin:  Var(MIC50): 0.5, MIC90: >16, RNG: (0.06–>16)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    chloramphenicol:  S(MIC50): 2, MIC90: 8, RNG: (0.25–32)
    metronidazole:  S(MIC50): 0.25, MIC90: 0.5, RNG: (0.06–1)
    clindamycin:  Var(MIC50): 0.25, MIC90: >32, RNG: (0.06->32)

    References

    SPECIFIC REFERENCES FOR DESULFOVIBRIO PIGER
  • Loubinoux2002 - Reclassification of the only species of the genus Desulfomonas, Desulfomonas pigra, as Desulfovibrio piger comb. nov.
  • Moore1976 - Emendation of Bacteroidaceae and Butyrivibrio and Descriptions of Desulfomonas gen. nov. and Ten New Species in the Genera Desulfomonas, Butyrivibrio, Eubacterium, Clostridium, and Ruminococcus.
  • Kuever2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Desulfovibrionaceae, Genus I. Desulfovibrio
  • Doumatey2020 - Gut Microbiome Profiles Are Associated With Type 2 Diabetes in Urban Africans
  • Finegold2010 - Pyrosequencing study of fecal microflora of autistic and control children
  • Finegold2012 - Microbiology of regressive autism
  • Lozupone2013 - Alterations in the gut microbiota associated with HIV-1 infection
  • Goldstein2006 - In vitro activity of moxifloxacin against 923 anaerobes isolated from human intra-abdominal infections.
  • Goldstein2000a - Comparative In vitro activities of ertapenem (MK-0826) against 1,001 anaerobes isolated from human intra-abdominal infections.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR DESULFOVIBRIO PIGER
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Chen2020 - Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine
  • Chen2020a - Featured Gut Microbiomes Associated With the Progression of Chronic Hepatitis B Disease
  • Chung2016 - Modulation of the human gut microbiota by dietary fibres occurs at the species level.
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Jie2017 - The gut microbiome in atherosclerotic cardiovascular disease
  • Karlsson2013 - Gut metagenome in European women with normal, impaired and diabetic glucose control
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Nielsen2014 - MetaHIT Consortium. Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Rothschild2018 - Environment dominates over host genetics in shaping human gut microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Walker2011 - High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel disease.
  • Wang2018 - A metagenome-wide association study of gut microbiota in asthma in UK adults
  • Wang2018a - Morphine induces changes in the gut microbiome and metabolome in a morphine dependence model.
  • Wang2020a - Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: April 08, 2021