Desulfovibrio vulgaris

(aka Desulfovibrio vulgaris subsp. vulgaris)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Desulfovibrio vulgaris, (aka Desulfovibrio vulgaris subsp. vulgaris), is a Gram-negative, non-spore-forming, strictly anaerobic, motile, vibrio bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 61.2%. Desulfovibrio vulgaris is probably a rare gut coloniser. (Postgate1966; Kuever2005Bergey)



  • This organism has been recovered from soil and water sources. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Uses sulfate, sulfite and thiosulfate as electron acceptors
    • GENERAL CHARACTERISTICS (Postgate1966); (Kuever2005Bergey);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 30-36℃.
  • ⥅
  • Substrates assimilated or utilised:
  • ethanol; methanol; propanol; formate; fumarate; lactate; malate; pyruvate;
  • ±
  • Strain-dependent substrate utilisation:
  • succinate;
    • SPECIAL FEATURES (Postgate1966); (Kuever2005Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate; H₂S;
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Nitrite:
  • not reduced
  • ✓
  • Sulfate:
  • reduced
  • ✓
  • Thiosulfate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Goldstein2006);
    Class Active Resistant
  • Cephalosporins:
  • cefoxitin;
  • Heterocycles:
  • metronidazole;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Deltaproteobacteria Order:  Desulfovibrionales Family:  Desulfovibrionaceae Genus:  Desulfovibrio Alt. name:  Desulfovibrio vulgaris subsp. vulgaris Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Vibrio
    Health:  Unknown
    Source:  soil and water sources
    DNA G+C(%):  61.2
    Opt. T:  30-36℃
    NaCl 0.5-2%:  0(+)
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Ethanol:  + Methanol:  + Propanol:  + Acetate:  neg Formate:  + Fumarate:  + Lactate:  + Malate:  + Pyruvate:  + Succinate:  d
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  + H2S:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amp-sulb:  Var(MIC50): 8, MIC90: 32, RNG: (0.06–32)
    cefoxitin:  R(MIC50): 64, MIC90: 128, RNG: (1–128)
    levofloxacin:  Var(MIC50): 0.5, MIC90: >16, RNG: (0.06–>16)
    moxifloxacin:  Var(MIC50): 0.5, MIC90: >16, RNG: (0.06–>16)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    metronidazole:  S(MIC50): 0.25, MIC90: 0.5, RNG: (0.06–1)
    clindamycin:  S(MIC50): 0.25, MIC90: 1, RNG: (0.06–>32)

    References

    SPECIFIC REFERENCES FOR DESULFOVIBRIO VULGARIS
  • Postgate1966 - Classification of Desulfovibrio species, the nonsporulating sulfate-reducing bacteria.
  • Kuever2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Desulfovibrionaceae, Genus I. Desulfovibrio
  • Goldstein2006 - In vitro activity of moxifloxacin against 923 anaerobes isolated from human intra-abdominal infections.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR DESULFOVIBRIO VULGARIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: January 14, 2022