Dialister hominis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Dialister hominis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 48.2%. Dialister hominis is probably a rare gut coloniser. (Sakamoto2020a)



  • This organism has been recovered from human faeces (Sakamoto2020a). Pathogenicity status unknown, or very unlikely to be pathogenic. Is a known gut commensal. Robust growth can have positive consequences for gut health.
    • GENERAL CHARACTERISTICS (Sakamoto2020a);
    Character Response
  • 💧
  • Bile tolerance:
  • Doesn't tolerate 20% bile
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 37℃; Grows optimally at 37℃.
  • ⥅
  • Substrates assimilated or utilised:
  • succinate;
  • Active enzymes:
  • acid phosphatase; esterase; naphthol-ASBI-P;
    • SPECIAL FEATURES (Sakamoto2020a);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (minor); propionate (major);
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Sakamoto2020a);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; penicillin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • oxytetracycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin; kanamycin;
  • neomycin; streptomycin;
  • Polypep/ketides:
  • bacitracin;
  • Heterocycles:
  • chloramphenicol;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Negativicutes Order:  Veillonellales Family:  Veillonellaceae Genus:  Dialister Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:   Positive
    Source:  human faeces (Sakamoto2020a)
    DNA G+C(%):  48.2
    Opt. T:  37℃
    Lower T(℃):  30(+)
    Mid T(℃):  37(+)
    Bile reaction(%):  20(neg)
    		Aesculin:  neg Gelatin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg AlanineAA:  neg CystineAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  neg PheAA:  neg SerAA:  neg TyrAA:  neg ValAA:  w AlkalineP:  neg AcidP:  + Esterase:  + EstLip(C8):  w Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  minor(+) Propionate:  Major(+) Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(25; disc)
    penicillin:  S(10U)
    gentamicin:  S(10; disc)
    kanamycin:  S(30; disc)
    neomycin:  R(30; disc)
    streptomycin:  R(10; disc)
    erythromycin:  S(15; disc)
    ciprofloxacin:  S(5; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    oxytetracycline:  S(30; disc)
    vancomycin:  R(30; disc)
    bacitracin:  S(10U)
    chloramphenicol:  S(30; disc)
    colistin:  S(10; disc)

    References

    SPECIFIC REFERENCES FOR DIALISTER HOMINIS
  • Sakamoto2020a - Dialister hominis sp. nov., isolated from human faeces.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR DIALISTER HOMINIS
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • GENERAL REFERENCES FOR DIALISTER HOMINIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: July 12, 2021