Dysgonomonas massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Dysgonomonas massiliensis is a Gram-negative, non-spore-forming, facultatively anaerobic, non-motile, coccobacillus bacterium. The DNA G+C content is 37.3%. Dysgonomonas massiliensis is probably a rare gut coloniser. (Bilen2019)



  • This organism has been recovered from human faeces (CCUG). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Bilen2019);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 4.9% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 37℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • D-arabinose; L-arabinose; fructose; galactose; glucose; mannose; xylose; amygdalin; aesculin; glycogen; starch; gentiobiose; lactose; maltose; mannitol; arbutin; gluconate; N-Ac glucosamine; salicin;
  • Active enzymes:
  • N-Ac β-glucosaminidase; catalase; chymotrypsin; esterase C4; esterase lipase C8; α-galactosidase; α-glucosidase; β-glucosidase; lipase C14; Val arylamidase; naphthol-ASBI-P;
    • RESPONSE TO ANTIBIOTICS (Bilen2019);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; benzylpenicillin; ertapenem; imipenem;
  • Tetracyclines:
  • doxycycline;
  • Aminoglycosides:
  • amikacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • fosfomycin;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • daptomycin; colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Dysgonomonadaceae Genus:  Dysgonomonas Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human faeces (CCUG)
    DNA G+C(%):  37.3
    Opt. T:  37℃
    Lower T(℃):  25(+)
    Mid T(℃):  37(+)
    NaCl 3-5%:  4.9(+)
    pH 6.0-8.0:  6(+)
    pH >8:  8.5(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  + L-Arabinose:  + Fructose:  + Galactose:  + Glucose:  + Mannose:  + Xylose:  + Gentiobiose:  + Lactose:  + Maltose:  + Amygdalin:  + Aesculin:  + Glycogen:  + Starch:  + Mannitol:  + Arbutin:  + Gluconate:  + NAc-α-GA:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Ac-β-glcamnd:  + α-Galactosidase:  + β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  + Chymotrypsin:  + ValAA:  + AlkalineP:  neg Esterase(C4):  + EstLip(C8):  + Lipase(C14):  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(0.023)
    benzyl-pen:  S(0.032)
    ertapenem:  S(0.016)
    imipenem:  S(0.094)
    amikacin:  R(>256)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  R(24)
    minocycline:  Var(MIC50): 16), MIC90: Var(16
    teicoplanin:  Var(MIC50): 3), MIC90: Var(3
    vancomycin:  R(>32)
    rifampicin:  S(2)
    fosfomycin:  R(1024)
    metronidazole:  S(1.5)
    daptomycin:  R(>256)
    colistin:  R(>256)

    References

    SPECIFIC REFERENCES FOR DYSGONOMONAS MASSILIENSIS
  • Bilen2019 - Dysgonomonas massiliensis sp. nov., a new species isolated from the human gut and its taxonogenomic description.
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    • GENERAL REFERENCES FOR DYSGONOMONAS MASSILIENSIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: July 12, 2021