Edwardsiella tarda

(aka Paracolobactrum anguillimortiferum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Edwardsiella tarda, (aka Paracolobactrum anguillimortiferum), is a Gram-negative, non-spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 7 gut microbiome compilation studies or metastudies. The DNA G+C content is 55-58%. Edwardsiella tarda is probably a common, although minor, coloniser of the gut. (Farmer1985; Bascomb1971; Sakazaki2005Bergey; Hoshina1962)



  • This organism has been recovered from human faeces, disease of fish and atherosclerotic plaques. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). Is a known human pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Farmer1985); (Bascomb1971); (Sakazaki2005Bergey); (Hoshina1962);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 5; tolerates pH 6.0-8.0; tolerates pH 10.8; Grows optimally at pH 7.2.
  • 🌡
  • Temperature tolerance:
  • grows at 15℃; grows at 40℃; Grows optimally at 30-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; maltose;
  • ⥅
  • Substrates assimilated or utilised:
  • aspartate; glutamate; isoleucine; phenylalanine; threonine; valine; glutamine;
  • Active enzymes:
  • arginine dihydrolase;
    • SPECIAL FEATURES (Farmer1985); (Bascomb1971); (Sakazaki2005Bergey); (Hoshina1962);
    Character Response
  • ✓
  • Metabolites produced:
  • Hâ‚‚S; indole;
  • ✗
  • Metabolites not produced:
  • ammonia;
  • ✗
  • VP test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
  • ✓
  • NO3➔NO2:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Sakazaki2005Bergey);
    Class Active Resistant
  • Penicillins:
  • ampicillin; ampicillin-sulbactam; carbenicillin; penicillin; penicillin G; piperacillin-tazobactam;
  • Cephalosporins:
  • cefdinir; cefoperazone; cefotiam; ceftazidime;
  • Macrolides:
  • clarithromycin; erythromycin; roxithromycin;
  • Tetracyclines:
  • tetracycline;
  • Quinolines:
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; kanamycin; streptomycin;
  • Heterocycles:
  • chloramphenicol; sulfadiazine;
  • fusidic-acid; sulfamethoxazole; trimethoprim;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • vibriostatin A 0 129;
  • colistin; polymyxin B;

  • Ewing, W. H., Mcwhorter, A. C., Escobar, M. R., & Lubin, A. H. (1965). Edwardsiella, a new genus of Enterobacteriaceae based on a new species, E. tarda. International Journal of Systematic Bacteriology, 15(1), 33–38.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Enterobacterales Family:  Enterobacteriaceae Genus:  Edwardsiella Alt. name:  Paracolobactrum anguillimortiferum Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod
    Health:  Unknown
    Source:  human faeces, disease of fish and atherosclerotic plaques
    DNA G+C(%):  55-58
    Opt. T:  30-37℃
    Low T(℃):  15(+)
    Mid T(℃):  40(+)
    Opt. pH:  7.2
    pH 4.2-5.9:  5(+)
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  10.8(+)
    		Aesculin:  neg Urea:  vr Gelatin:  neg Starch:  neg Hippurate:  neg Milk:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg L-Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  + Melezitose:  neg Sucrose:  neg Trehalose:  neg Dextrin:  neg Aesculin:  neg Glycogen:  neg Inulin:  neg Starch:  neg D-Arabitol:  neg Glycerol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Asp:  + Glu:  + Ile:  + Phe:  + Thr:  + Val:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg β-Mannosidase:  neg ArgDH:  + GluDC:  vr AlanineAA:  neg AlaPheProAA:  neg GluGluAA:  neg GlyAA:  neg LeuAA:  neg LeuGlyAA:  neg PyrrolidAA:  neg AlkalineP:  neg AcidP:  vr Esterase(C4):  vr EstLip(C8):  vr Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  + Ammonia:  neg Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  RNG: (0.13-64)
    Augmentin:  RNG: (0.06-4)
    ampicillin:  Sens
    amp-sulb:  SensRNG: (0.06-2)
    azlocillin:  RNG: (0.25-8)
    carbenicil:  Sens
    mezlocillin:  RNG: (0.13-4)
    oxacillin:  RNG: (≤0.03->128)
    penicillin:  SensRNG: (0.5-32)
    penicillin_G:  Sens
    piperacillin:  RNG: (0.13-4)
    piper-taz:  SensRNG: (0.13-0.25)
    ticarcillin:  RNG: (0.13-32)
    cefaclor:  RNG: (0.13-8)
    cefdinir:  SensRNG: (≤0.03-0.5)
    cefoperazone:  SensRNG: (≤0.03-2)
    cefotiam:  SensRNG: (≤0.03-0.5)
    cefoxitin:  RNG: (0.25-4)
    ceftazidime:  SensRNG: (≤0.03-0.5)
    cefuroxime:  RNG: (≤0.03-4)
    gentamicin:  Sens
    kanamycin:  Sens
    streptomycin:  Sens
    azithromycin:  RNG: (4-16)
    erythromycin:  R(8-64)
    clarithromycin:  R(8-32)
    roxithromycin:  R(32->128)
    nalidixic-acid:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  RNG: (0.25->128)
    minocycline:  RNG: (0.25-8)
    tetracycline:  SensRNG: (0.5->128)
    vancomycin:  R(32->128)
    chloramphenicol:  Sens
    fosfomycin:  RNG: (0.5-32)
    nitrofurantoin:  RNG: (4-8)
    sulfadiazine:  Sens
    sulfamethoxazole:  R(5000)
    trimethoprim:  R(312.5)
    clindamycin:  RNG: (4-64)
    colistin:  Res
    polymyxin_B:  Res
    fusidic-acid:  R(32-64)
    vibriostat_129:  Sens

    References

    SPECIFIC REFERENCES FOR EDWARDSIELLA TARDA
  • Farmer1985 - Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens.
  • Bascomb1971 - Numerical Classification of the Tribe Klebsielleae.
  • Sakazaki2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Gammaproteobacteria Part B. Family Enterobacteriaceae, Genus XI. Edwardsiella
  • SelberHnatiw2020 - Metabolic networks of the human gut microbiota.
  • Hoshina1962 - On a New Bacterium, Paracolobactrum Anguillimortiferum n. sp.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR EDWARDSIELLA TARDA
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Forster2019 - A human gut bacterial genome and culture collection for improved metagenomic analyses.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Tyakht2013 - Human gut microbiota community structures in urban and rural populations in Russia.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • GENERAL REFERENCES FOR EDWARDSIELLA TARDA
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021