Eggerthella sinensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Eggerthella sinensis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 65%. Eggerthella sinensis is probably a rare gut coloniser. (Lau2004; Maruo2008; Wade2005Bergey)



  • This organism has been recovered from human gut, and patient with proctitis (Alkhalil2017). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread (notes: opportunistic in immunocompromised patients). Is a rare opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Lau2004); (Maruo2008); (Wade2005Bergey);
    Character Response
  • ⥅
  • Substrates assimilated or utilised:
  • arginine;
  • Active enzymes:
  • arginine dihydrolase; catalase;
    • SPECIAL FEATURES (Lau2004); (Maruo2008);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • Nitrate:
  • reduction is variable
    • RESPONSE TO ANTIBIOTICS (Lau2004);
    Class Active Resistant
  • Penicillins:
  • penicillin;
  • Cephalosporins:
  • cefotaxime;
  • Heterocycles:
  • metronidazole;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Eggerthellales Family:  Eggerthellaceae Genus:  Eggerthella Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human gut, and patient with proctitis (Alkhalil2017)
    DNA G+C(%):  65
    		Urea:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Glucose:  neg Mannose:  neg Xylose:  neg Trehalose:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arg:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  + Urease:  neg α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg Xylosidase:  neg ArgDH:  + GluDC:  neg AlanineAA:  neg GluGluAA:  neg GlyAA:  neg HisAA:  neg LeuAA:  neg LeuGlyAA:  neg ProAA:  neg PheAA:  neg PyrogluAA:  neg SerAA:  neg TyrAA:  neg AlkalineP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin:  S(0.5)
    cefotaxime:  S(0.25)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Var(MIC50): 3), MIC90: Var(3
    metronidazole:  S(0.25)

    References

    SPECIFIC REFERENCES FOR EGGERTHELLA SINENSIS
  • Lau2004 - Eggerthella hongkongensis sp. nov. and eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia.
  • Maruo2008 - Adlercreutzia equolifaciens gen. nov., sp. nov., an equol-producing bacterium isolated from human faeces, and emended description of the genus Eggerthella.
  • Wade2005Bergey - Bergey's manual of systematic bacteriology. Vol. 5, The Actinobacteria. Part A & B. Coriobacteriaceae, Genus VI. Eggerthella
  • Wang2019d - Gut Microbiota Dysbiosis Is Associated with Altered Bile Acid Metabolism in Infantile Cholestasis
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR EGGERTHELLA SINENSIS
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • ...............................
    • GENERAL REFERENCES FOR EGGERTHELLA SINENSIS
  • Alkhalil2017 - Bacterial involvements in ulcerative colitis: molecular and microbiological studies
    • Added: December 15, 2021