Eggerthella timonensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Eggerthella timonensis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 65.2%. Eggerthella timonensis is probably a rare gut coloniser. (Bilen2017b; Bilen2018b)



  • This organism has been recovered from human faeces (CCUG). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Bilen2018b);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-8.0; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 42℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; fucose; galactose; glucose; mannose; rhamnose; ribose; D-tagatose; xylose; amygdalin; aesculin; starch; cellubiose; gentiobiose; lactose; maltose; melezitose; melibiose; raffinose; sucrose; trehalose; D-arabitol; glycerol; mannitol; sorbitol; arbutin; 2-ketogluconate; 5-ketogluconate; methyl mannoside; N-Ac glucosamine; salicin;
  • Active enzymes:
  • acid phosphatase; catalase; esterase C4; esterase lipase C8;
    • SPECIAL FEATURES (Bilen2018b);
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
    • RESPONSE TO ANTIBIOTICS (Bilen2018b);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; benzylpenicillin; imipenem;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • minocycline; tigecycline;
  • Aminoglycosides:
  • amikacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • daptomycin; colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Eggerthellales Family:  Eggerthellaceae Genus:  Eggerthella Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (CCUG)
    DNA G+C(%):  65.2
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  42(+)
    NaCl 3-5%:  5(+)
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  8.5(+)
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  + Fructose:  + Fucose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Ribose:  + D-Tagatose:  + Xylose:  + Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  + Melibiose:  + Sucrose:  + Trehalose:  + Amygdalin:  + Aesculin:  + Starch:  + D-Arabitol:  + Glycerol:  + Mannitol:  + Sorbitol:  + Arbutin:  + 2-Ketogluconate:  + 5-Ketogluconate:  + Me-α-D-Mann:  + NAc-α-GA:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg β-Galactosidase:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(0.75)
    benzyl-pen:  S(1.5)
    imipenem:  S(0.94)
    amikacin:  R(256)
    erythromycin:  S(0.016)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    minocycline:  S(0.38)
    tigecycline:  S(0.25)
    teicoplanin:  S(0.125)
    vancomycin:  S(1.5)
    rifampicin:  S(0.047)
    metronidazole:  S(0.19)
    daptomycin:  R(64)
    colistin:  R(256)

    References

    SPECIFIC REFERENCES FOR EGGERTHELLA TIMONENSIS
  • Bilen2017b - 'Eggerthella timonensis' gen. nov. isolated from a human stool sample.
  • Bilen2018b - Eggerthella timonensis sp. nov, a new species isolated from the stool sample of a pygmy female.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR EGGERTHELLA TIMONENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • GENERAL REFERENCES FOR EGGERTHELLA TIMONENSIS
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: July 12, 2021