Elizabethkingia meningoseptica

(aka Flavobacterium meningosepticum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Elizabethkingia meningoseptica, (aka Flavobacterium meningosepticum), is a Gram-negative, non-spore-forming, strictly aerobic, non-motile, rod-shaped - curved bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 37.2%. Elizabethkingia meningoseptica is likely to be transient and not a long-term gut coloniser. (Kim2005; King1959; Bruun2010Bergey)



  • This organism has been recovered from throat and clinical sources (blood, wound, respiratory tract - CCUG). The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: pathogen of humans and vertebrates). It is an opportunistic pathogen. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Obligate aerobe; unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Kim2005); (King1959); (Bruun2010Bergey);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; casein; gelatin;
  • 🌡
  • Temperature tolerance:
  • grows at 22℃; doesn't grow at 42℃; Grows optimally at 30-37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; glucose; mannose; lactose; maltose; trehalose; glycerol; mannitol;
  • ±
  • Strain-dependent acid from carbs:
  • melibiose;
  • ⥅
  • Substrates assimilated or utilised:
  • 3-hydroxybutyrate;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; N-Ac β-glucosaminidase; catalase; cystine arylamidase; esterase lipase C8; α-galactosidase; α-glucosidase; Leu arylamidase; oxidase; trypsin; Val arylamidase; naphthol-ASBI-P;
  • ±
  • Strain-dependent active enzymes:
  • fucosidase; β-galactosidase;
    • SPECIAL FEATURES (Kim2005); (King1959); (Bruun2010Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • indole (weak);
  • ✗
  • Metabolites not produced:
  • H₂S;
  • ✗
  • VP test:
  • not active
  • ✗
  • Haemolysis:
  • absent
  • ✗
  • Nitrate:
  • not reduced
  • Pigments:
  • yellow (variable)
    • RESPONSE TO ANTIBIOTICS (King1959); (Bruun2010Bergey);
    Class Active Resistant
  • Penicillins:
  • ampicillin; imipenem; meropenem; penicillin;
  • Cephalosporins:
  • cefepime; cefotaxime; ceftazidime;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • minocycline;
  • chlortetracycline; oxytetracycline; tetracycline;
  • Quinolines:
  • gatifloxacin; levofloxacin; moxifloxacin; sparfloxacin;
  • Aminoglycosides:
  • gentamicin; neomycin; streptomycin;
  • Polypep/ketides:
  • rifampicin;
  • bacitracin;
  • Heterocycles:
  • nitrofurantoin;
  • Miscellaneous antibiotics:
  • polymyxin B;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Flavobacteriia Order:  Flavobacteriales Family:  Weeksellaceae Genus:  Elizabethkingia Alt. name:  Flavobacterium meningosepticum Gram stain:  neg O2 Relation.:  strictly aerobic Spore:  No spore Motility:  Sessile Morphology:  Rod - curved Pigment:  yellow (variable)
    Health:  Unknown
    Source:  throat and clinical sources (blood, wound, respiratory tract - CCUG)
    DNA G+C(%):  37.2
    Opt. T:  30-37℃
    Lower T(℃):  22(+)
    High T(℃):  42(neg)
    		Aesculin:  + Urea:  neg Gelatin:  + Starch:  neg Casein:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  w(+) Galactose:  neg Glucose:  w(+) Mannose:  w(+) Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  w(+) Maltose:  w(+) Melibiose:  d Sucrose:  neg Trehalose:  w(+) Adonitol:  neg Dulcitol:  neg Glycerol:  w(+) Mannitol:  w(+) Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Citrate:  vr 3-Hydroxybutyrate:  + Malonate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg Ac-β-glcamnd:  + α-Fucosidase:  d α-Galactosidase:  d(+) β-Galactosidase:  d(neg) α-Glucosidase:  + β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  neg Trypsin:  + CystineAA:  + LeuAA:  + ValAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  neg EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  w Pigment:  yellow (variable)
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Res
    penicillin:  Res
    imipenem:  Res
    meropenem:  Res
    cefepime:  Res
    cefotaxime:  Res
    ceftazidime:  Res
    gentamicin:  Res
    neomycin:  Res
    streptomycin:  R(100)
    erythromycin:  Sens
    ciprofloxacin:  Var
    gatifloxacin:  Sens
    levofloxacin:  Sens
    moxifloxacin:  Sens
    sparfloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    chlortetracycline:  Res
    minocycline:  Sens
    oxytetracycline:  Res
    tetracycline:  Res
    bacitracin:  Res
    rifampicin:  Sens
    chloramphenicol:  Var
    nitrofurantoin:  Res
    polymyxin_B:  Res

    References

    SPECIFIC REFERENCES FOR ELIZABETHKINGIA MENINGOSEPTICA
  • Kim2005 - Transfer of Chryseobacterium meningosepticum and Chryseobacterium miricola to Elizabethkingia gen. nov. as Elizabethkingia meningoseptica comb. nov. and Elizabethkingia miricola comb. nov.
  • King1959 - Studies on a Group of Previously Unclassified Bacteria Associated with Meningitis in Infants.
  • Vandamme1994 - Notes: New Perspectives in the Classification of the Flavobacteria: Description of Chryseobacterium gen. nov., Bergeyella gen. nov., and Empedobacter nom. rev.
  • Bruun2010Bergey - Bergey's manual of systematic bacteriology. Vol. 4, The Fusobacteria. Family Flavobacteriaceae, Genus XVII. Elizabethkingia
  • Cassir2015 - Clostridium butyricum Strains and Dysbiosis Linked to Necrotizing Enterocolitis in Preterm Neonates
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ELIZABETHKINGIA MENINGOSEPTICA
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: July 12, 2021