General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview


  • Enorma timonensis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 65.8%. Enorma timonensis is probably a rare gut coloniser. (Ramasamy2014a)



  • This organism has been recovered from human faeces (Ramasamy2014a). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.

  • GENERAL CHARACTERISTICS (Ramasamy2014a);
    Character Response
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 30℃; grows at 37℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • Active enzymes:
  • cystine arylamidase; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase; His arylamidase; Leu arylamidase; Phe arylamidase; Pro arylamidase; Ser arylamidase; Val arylamidase; naphthol-ASBI-P;

  • SPECIAL FEATURES (Ramasamy2014a);
    Character Response
  • Metabolites not produced:
  • indole;
  • Nitrate:
  • not reduced

  • RESPONSE TO ANTIBIOTICS (Ramasamy2014a);
    Class Active Resistant
  • Penicillins:
  • amoxicillin-clavulanic acid; imipenem;
  • amoxicillin; penicillin G;
  • Macrolides:
  • erythromycin;
  • Aminoglycosides:
  • gentamicin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole;
  • trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

  • Details


    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Coriobacteriales Family:  Coriobacteriaceae Genus:  Enorma Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces (Ramasamy2014a)
    DNA G+C(%):  65.8
    Opt. T:  37℃
    Lower T(℃):  30(neg)
    Mid T(℃):  37(+)
    High T(℃):  45(neg)

    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  neg D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Amygdalin:  neg Aesculin:  neg Glycogen:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  neg

    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Mannose:  neg

    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + α-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg GluDC:  neg Trypsin:  neg AlanineAA:  neg ArgAA:  neg CystineAA:  + GlyAA:  neg HisAA:  + LeuAA:  + LeuGlyAA:  neg ProAA:  + PheAA:  + SerAA:  + TyrAA:  neg ValAA:  + AlkalineP:  neg AcidP:  neg Esterase(C4):  neg EstLip(C8):  neg Lipase(C14):  neg

    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    Indole:  neg

    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Res
    Augmentin:  Sens
    penicillin_G:  Res
    imipenem:  Sens
    gentamicin:  Sens
    erythromycin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  Sens
    rifampicin:  Sens
    metronidazole:  Sens
    SXT:  Res

    References


    SPECIFIC REFERENCES FOR ENORMA TIMONENSIS
  • Ramasamy2014a - Non contiguous-finished genome sequence and description of Enorma timonensis sp. nov.
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  • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ENORMA TIMONENSIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
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