Enterococcus malodoratus

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Enterococcus malodoratus is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 40-41%. Enterococcus malodoratus is probably a rare gut coloniser. (Collins1984; Rossi2016)



  • This organism has been recovered from animal sources, cheese, clinical sources (blood, abscess - CCUG) and has been detected in human faeces (Bilen2018e). The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Collins1984);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🧂
  • Salt tolerance:
  • tolerates 6.5% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 45℃;
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; rhamnose; ribose; sorbose; D-tagatose; amygdalin; cellubiose; gentiobiose; lactose; maltose; melibiose; raffinose; sucrose; trehalose; adonitol; D-arabitol; L-arabitol; dulcitol; mannitol; sorbitol; xylitol; arbutin; gluconate; 2-ketogluconate; methyl mannoside; N-Ac glucosamine; salicin;
  • Active enzymes:
  • α-galactosidase; β-galactosidase;
    • SPECIAL FEATURES (Collins1984);
    Character Response
  • ✓
  • Metabolites produced:
  • lactate; H₂S;
  • ✗
  • VP test:
  • not active
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Goldstein2000);
    Class Active Resistant
  • Penicillins:
  • penicillin G;
  • Macrolides:
  • erythromycin;
  • Quinolines:
  • levofloxacin; moxifloxacin;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Enterococcaceae Genus:  Enterococcus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus Pigment:  neg
    Health:  Unknown
    Source:  animal sources, cheese, clinical sources (blood, abscess - CCUG) and has been detected in human faeces (Bilen2018e)
    DNA G+C(%):  40-41
    High T(℃):  45(neg)
    NaCl >6%:  6.5(+)
    		Aesculin:  + Hippurate:  vr
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  + Ribose:  + Sorbose:  + D-Tagatose:  + Xylose:  vr L-Xylose:  vr Cellubiose:  + Gentiobiose:  + Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  vr Amygdalin:  + Glycogen:  neg Inulin:  neg Adonitol:  + D-Arabitol:  + L-Arabitol:  + Dulcitol:  + Erythritol:  neg Glycerol:  vr Inositol:  neg Mannitol:  + Sorbitol:  + Xylitol:  + Arbutin:  + Gluconate:  + 2-Ketogluconate:  + 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  + Me-Xyloside:  neg NAc-α-GA:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg α-Galactosidase:  + β-Galactosidase:  + β-Glucuronidase:  neg ArgDH:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Lactate:  + H2S:  + Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    penicillin_G:  S(MIC50): 0.25, MIC90: 2, RNG: (≤0.015–2)
    azithromycin:  Var(MIC50): 0.25, MIC90: >32, RNG: (0.06–>32)
    erythromycin:  S(MIC50): 0.06, MIC90: 0.128, RNG: (≤0.015–.128)
    levofloxacin:  S(MIC50): 1, MIC90: 1, RNG: (0.25–1)
    moxifloxacin:  S(MIC50): 0.25, MIC90: 0.25, RNG: (0.06–0.5)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Var(MIC50): 0.25, MIC90: 16, RNG: (0.06–32)
    minocycline:  Var(MIC50): 0.06, MIC90: 16, RNG: (≤0.015–16)
    tetracycline:  Var(MIC50): 0.5, MIC90: >32, RNG: (0.125–>32)
    vancomycin:  S(MIC50): 0.5, MIC90: 2, RNG: (0.125–2)

    References

    SPECIFIC REFERENCES FOR ENTEROCOCCUS MALODORATUS
  • Collins1984 - Enterococcus avium nom. rev., comb. nov.: E. casseliflavus nom. rev., comb. nov.: E. durans nom. rev., comb. nov.: E. gallinarum comb. nov.: and E. malodoratus sp. nov.
  • Rossi2016 - Mining metagenomic whole genome sequences revealed subdominant but constant Lactobacillus population in the human gut microbiota.
  • Goldstein2000 - Comparative in vitro activities of GAR-936 against aerobic and anaerobic animal and human bite wound pathogens.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ENTEROCOCCUS MALODORATUS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • GENERAL REFERENCES FOR ENTEROCOCCUS MALODORATUS
  • Bilen2018e - Description of the human gut microbiota by culturomics
    • Added: January 06, 2022