Enterococcus timonensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Enterococcus timonensis is a Gram-positive, non-spore-forming, facultatively anaerobic, motile, coccus bacterium. The DNA G+C content is 38.5%. Enterococcus timonensis is probably a rare gut coloniser. (Fonkou2018a; Fonkou2019)



  • This organism has been recovered from human faeces and sputum (healthy). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Fonkou2018a); (Fonkou2019);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin; gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 0.5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-8.0; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; aesculin; cellubiose; lactose; maltose; sucrose; trehalose; glycerol; mannitol; N-Ac glucosamine; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • gluconate; mannitol; mannose;
  • Active enzymes:
  • alkaline phosphatase; acid phosphatase; chymotrypsin; cystine arylamidase; esterase C4; esterase lipase C8; fucosidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucuronidase; Leu arylamidase; lipase C14; α-mannosidase; Val arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Fonkou2019);
    Class Active Resistant
  • Penicillins:
  • amoxicillin;
  • ertapenem;
  • Cephalosporins:
  • cefotaxime;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline; minocycline;
  • Aminoglycosides:
  • amikacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • fosfomycin; metronidazole;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • daptomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Enterococcaceae Genus:  Enterococcus Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Swimming Morphology:  Coccus
    Health:  Unknown
    Source:  human faeces and sputum (healthy)
    DNA G+C(%):  38.5
    Opt. T:  37℃
    Lower T(℃):  25(+)
    NaCl 0.5-2%:  0.5(+)
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  8.5(+)
    		Aesculin:  + Gelatin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  + Gentiobiose:  neg Lactose:  + Maltose:  + Melezitose:  neg Melibiose:  neg Sucrose:  + Trehalose:  + Turanose:  neg Amygdalin:  neg Aesculin:  + Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  + Inositol:  neg Mannitol:  + Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  + Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Arabinose:  neg Mannose:  + Maltose:  neg N_Acetyl_glucosamine:  neg Gluconate:  + Mannitol:  + Adipate:  neg Caprate:  neg Citrate:  neg Malate:  neg Phenylacetate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  neg β-Glucuronidase:  + α-Mannosidase:  + ArgDH:  neg Chymotrypsin:  + Trypsin:  neg CystineAA:  + LeuAA:  + ValAA:  + AlkalineP:  + AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  S(0.038)
    benzyl-pen:  Var(MIC50): 1), MIC90: Var(1, RNG: (0.016-256)
    ertapenem:  R(2)
    imipenem:  Var(MIC50): 1), MIC90: Var(1
    cefotaxime:  R(MIC50): 6), MIC90: R(6, RNG: (0.002-32)
    amikacin:  R(48)
    tobramycin:  Var(MIC50): 3), MIC90: Var(3
    erythromycin:  S(0.75)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  S(0.38)
    minocycline:  S(0.094)
    teicoplanin:  S(0.75)
    vancomycin:  S(1)
    rifampicin:  S(1)
    fosfomycin:  R(12)
    metronidazole:  R(256)
    daptomycin:  S(2)

    References

    SPECIFIC REFERENCES FOR ENTEROCOCCUS TIMONENSIS
  • Fonkou2018a - 'Enterococcus timonensis' sp. nov., 'Actinomyces marseillensis' sp. nov., 'Leptotrichia massiliensis' sp. nov., 'Actinomyces pacaensis' sp. nov., 'Actinomyces oralis' sp. nov., 'Actinomyces culturomici' sp. nov. and 'Gemella massiliensis' sp. nov., new bacterial species isolated from the human respiratory microbiome.
  • Fonkou2019 - Non-contiguous finished genome sequencing and description of Enterococcus timonensis sp. nov. isolated from human sputum.
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    • Added: April 08, 2023