Escherichia fergusonii

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Escherichia fergusonii is a Gram-negative, non-spore-forming, facultatively anaerobic, motile, rod-shaped bacterium. It has been detected in at least 9 gut microbiome compilation studies or metastudies. Escherichia fergusonii is probably a common, although minor, coloniser of the gut. (Farmer1985; Farmer1985a; Scheutz2005Bergey)



  • This organism has been recovered from human faeces, clinical sources (including atherosclerotic plaques) and raptors. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). Is a known human pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Farmer1985); (Farmer1985a); (Scheutz2005Bergey);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • arabinose; L-arabinose; galactose; glucose; mannose; rhamnose; xylose; amygdalin; cellubiose; maltose; trehalose; adonitol; D-arabitol; mannitol;
  • ±
  • Strain-dependent acid from carbs:
  • dulcitol;
  • ⥅
  • Substrates assimilated or utilised:
  • acetate;
  • Active enzymes:
  • catalase; β-galactosidase; β-glucosidase; lycine decarboxylase; ornithine decarboxylase;
  • ±
  • Strain-dependent active enzymes:
  • arginine decarboxylase;
    • SPECIAL FEATURES (Farmer1985); (Farmer1985a); (Scheutz2005Bergey);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Metabolites not produced:
  • H₂S;
  • ✓
  • Methyl red test:
  • active
  • ✗
  • VP test:
  • not active
  • ±
  • ONPG test:
  • active for most strains
  • KCN growth:
  • inhibited
  • ✓
  • NO3➔NO2:
  • reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (Farmer1985a); (Scheutz2005Bergey);
    Class Active Resistant
  • Penicillins:
  • ampicillin; carbenicillin;
  • penicillin;
  • Cephalosporins:
  • cephalothin;
  • Quinolines:
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin;
  • Heterocycles:
  • chloramphenicol;
  • fusidic-acid;
  • Miscellaneous antibiotics:
  • colistin;

  • Farmer, J. J., 3rd, Fanning, G. R., Davis, B. R., O’Hara, C. M., Riddle, C., Hickman-Brenner, F. W., Asbury, M. A., Lowery, V. A., 3rd, & Brenner, D. J. (1985). Escherichia fergusonii and Enterobacter taylorae, two new species of Enterobacteriaceae isolated from clinical specimens. Journal of Clinical Microbiology, 21(1), 77–81.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Enterobacterales Family:  Enterobacteriaceae Genus:  Escherichia Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces, clinical sources (including atherosclerotic plaques) and raptors
    		Aesculin:  w Urea:  neg Gelatin:  neg Tyrosine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  + L-Arabinose:  + Galactose:  + Glucose:  + Mannose:  + Rhamnose:  + Xylose:  + Cellubiose:  + Lactose:  w Maltose:  + Melibiose:  neg Sucrose:  neg Trehalose:  + Amygdalin:  + Adonitol:  + D-Arabitol:  + L-Arabitol:  neg Dulcitol:  d Erythritol:  neg Glycerol:  w Inositol:  neg Mannitol:  + Sorbitol:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Salicin:  w
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  neg Acetate:  + Citrate:  w Malonate:  w
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  + Urease:  neg Ac-β-glcamnd:  neg α-Galactosidase:  neg β-Galactosidase:  + α-Glucosidase:  neg β-Glucosidase:  + β-Glucuronidase:  neg ArgDH:  neg ArgDC:  d(neg) LysDC:  + OrnDC:  + Phe deaminase:  neg DNAse:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  + Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  S(vr)
    carbenicil:  S(vr)
    penicillin:  Res
    cephalothin:  R(vr)
    gentamicin:  Sens
    streptomycin:  Var
    nalidixic-acid:  S(vr)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  Var
    chloramphenicol:  Sens
    sulfadiazine:  Var
    colistin:  Sens
    fusidic-acid:  Res

    References

    SPECIFIC REFERENCES FOR ESCHERICHIA FERGUSONII
  • Farmer1985 - Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens.
  • Farmer1985a - Escherichia fergusonii and Enterobacter taylorae, two new species of Enterobacteriaceae isolated from clinical specimens.
  • Scheutz2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Gammaproteobacteria Part B. Family Enterobacteriaceae, Genus I. Escherichia
  • SelberHnatiw2020 - Metabolic networks of the human gut microbiota.
  • Gryp2020 - Isolation and Quantification of Uremic Toxin Precursor-Generating Gut Bacteria in Chronic Kidney Disease Patients
  • Hedin2015 - Siblings of patients with Crohn's disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR ESCHERICHIA FERGUSONII
  • Almeida2019 - A new genomic blueprint of the human gut microbiota.
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Dubinkina2017 - Links of gut microbiota composition with alcohol dependence syndrome and alcoholic liver disease
  • Hu2019 - The Gut Microbiome Signatures Discriminate Healthy From Pulmonary Tuberculosis Patients
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Zou2019 - 1,520 reference genomes from cultivated human gut bacteria enable functional microbiome analyses.
  • Zupancic2012 - Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome.
  • ...............................
    • GENERAL REFERENCES FOR ESCHERICHIA FERGUSONII
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: April 08, 2021