Eubacterium cellulosolvens

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Eubacterium cellulosolvens is a Gram-positive, non-spore-forming, strictly anaerobic, motile, short rod-shaped bacterium. It has been detected in at least 8 gut microbiome compilation studies or metastudies. The DNA G+C content is 50%. Eubacterium cellulosolvens is probably a common, although minor, coloniser of the gut. (Bryant1958a; vanGylswyk1986; Wade2011Bergeys)



  • This organism has been recovered from human faeces, and cow and sheep rumen. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Cellulolytic.
    • GENERAL CHARACTERISTICS (Bryant1958a); (vanGylswyk1986); (Wade2011Bergeys);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • ±
  • Strain-dependent hydrolysis or digestion:
  • pectin;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 6.5% salt;
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 9.6;
  • 🌡
  • Temperature tolerance:
  • grows weakly at 30℃; grows at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; cellulose; aesculin; inulin; pectin; cellubiose; lactose; maltose; raffinose; sucrose; salicin;
  • ±
  • Strain-dependent acid from carbs:
  • melezitose;
    • SPECIAL FEATURES (Bryant1958a); (vanGylswyk1986); (Wade2011Bergeys);
    Character Response
  • ✓
  • Metabolites produced:
  • formate (trace); acetate; butyrate; lactate (major); succinate (trace); Hâ‚‚ (trace);
  • ✗
  • Metabolites not produced:
  • Hâ‚‚S; indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced

  • Finegold, S. M., Sutter, V. L., Sugihara, P. T., Elder, H. A., Lehmann, S. M., & Phillips, R. L. (1977). Fecal microbial flora in Seventh Day Adventist populations and control subjects. The American Journal of Clinical Nutrition, 30(11), 1781–1792.

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Eubacteriaceae Genus:  Eubacterium Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Short Rod Pigment:  neg
    Health:  Unknown
    Source:  human faeces, and cow and sheep rumen
    DNA G+C(%):  50
    Opt. T:  37℃
    Lower T(℃):  30(w)
    High T(℃):  45(+)
    NaCl >6%:  6.5(neg)
    pH >8:  9.6(neg)
    		Aesculin:  + Gelatin:  neg Starch:  neg Hippurate:  neg Milk:  w Meat:  neg Pectin:  d
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg L-Arabinose:  neg Fructose:  + Galactose:  + Glucose:  + Mannose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg Xylose:  neg Cellubiose:  + Lactose:  d(+) Maltose:  + Melezitose:  d Melibiose:  neg Sucrose:  w(+) Trehalose:  neg Amygdalin:  w Cellulose:  + Aesculin:  + Glycogen:  neg Inulin:  + Starch:  neg Pectin:  + Xylan:  neg Adonitol:  neg Dulcitol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Melibiose:  neg Lactate:  neg Pyruvate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  trace(+) Acetate:  + Butyrate:  + Lactate:  Major(+) Succinate:  trace(+) H2S:  neg H2:  trace(+) Indole:  neg Pigment:  neg

    References

    SPECIFIC REFERENCES FOR EUBACTERIUM CELLULOSOLVENS
  • Bryant1958a - Characteristics of ruminal anaerobic celluloytic cocci and Cillobacterium cellulosolvens n. sp.
  • vanGylswyk1986 - Description and Designation of a Neotype Strain of Eubacterium cellulosolvens (Cillobacterium cellulosolvens Bryant, Small, Bouma and Robinson) Holdeman and Moore.
  • Wade2011Bergeys - Bergey's manual of systematic bacteriology. Vol. 3, The Firmicutes. Family Eubacteriaceae, Genus I. Eubacterium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR EUBACTERIUM CELLULOSOLVENS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Finegold1977 - Fecal microbial flora in Seventh Day Adventist populations and control subjects.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Qin2012 - Metagenome-wide association study of gut microbiota in type 2 diabetes
  • RajilicStojanovic2014 - The first 1000 cultured species of the human gastrointestinal microbiota.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • Zupancic2012 - Analysis of the Gut Microbiota in the Old Order Amish and Its Relation to the Metabolic Syndrome.
  • ...............................
    • GENERAL REFERENCES FOR EUBACTERIUM CELLULOSOLVENS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: April 08, 2021