Eubacterium coprostanoligenes

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Eubacterium coprostanoligenes is a Gram-positive, non-spore-forming, anaerobic, non-motile, coccobacillus bacterium. It has been detected in at least 4 gut microbiome compilation studies or metastudies. The DNA G+C content is 41%. Eubacterium coprostanoligenes is probably a common, although minor, coloniser of the gut. (Freier1994)



  • This organism has been recovered from human faeces and pig sewage. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • In 38% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Freier1994);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 5.5; doesn't tolerate pH 8; Grows optimally at pH 7.0-7.5.
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 25℃; doesn't grow at 45℃; Grows optimally at 35℃.
  • H+
  • Acid from carbohydrates usually produced:
  • amygdalin; lactose; salicin;
  • Active enzymes:
  • β-glucosidase;
    • SPECIAL FEATURES (Freier1994);
    Character Response
  • ✓
  • Metabolites produced:
  • formate; acetate; succinate; CO₂ (minor); H₂;
  • ✗
  • Metabolites not produced:
  • ethanol; propanol; butanol; indole;
  • ✗
  • Nitrate:
  • not reduced

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Eubacteriaceae Genus:  Eubacterium Gram stain:  + O2 Relation.:  anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human faeces and pig sewage
    DNA G+C(%):  41
    Opt. T:  35℃
    Lower T(℃):  25(neg)
    High T(℃):  45(neg)
    Opt. pH:  7.0-7.5
    pH 4.2-5.9:  5.5(neg)
    pH 6.0-8.0:  8(neg)
    		Aesculin:  + Gelatin:  neg Starch:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  w Fructose:  w Glucose:  w Mannose:  w Cellubiose:  w Lactose:  + Melibiose:  w Amygdalin:  + Salicin:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    β-Glucosidase:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Formate:  + Acetate:  + Ethanol:  neg Propanol:  neg Butanol:  neg Succinate:  + CO2:  minor(+) H2:  + Indole:  neg

    References

    SPECIFIC REFERENCES FOR EUBACTERIUM COPROSTANOLIGENES
  • Freier1994 - Characterization of Eubacterium coprostanoligenes sp. nov., a cholesterol-reducing anaerobe.
  • Chen2019a - Association between fecal microbiota and generalized anxiety disorder: Severity and early treatment response
  • DeAngelis2013 - Fecal microbiota and metabolome of children with autism and pervasive developmental disorder not otherwise specified
  • Dong2020a - The Association of Gut Microbiota With Idiopathic Central Precocious Puberty in Girls
  • Feng2019a - Alterations in the gut microbiota and metabolite profiles of thyroid carcinoma patients
  • Li2019c - Gut Microbiota Differs Between Parkinson's Disease Patients and Healthy Controls in Northeast China
  • Lun2018 - Altered gut microbiota and microbial biomarkers associated with chronic kidney disease
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR EUBACTERIUM COPROSTANOLIGENES
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • De2020 - Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of microbial dark matter.
  • Minerbi2019 - Altered microbiome composition in individuals with fibromyalgia
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • GENERAL REFERENCES FOR EUBACTERIUM COPROSTANOLIGENES
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: December 15, 2021