Facklamia languida

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Facklamia languida is a Gram-positive, non-spore-forming, facultatively anaerobic, non-motile, oval-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. Facklamia languida is probably a rare gut coloniser. (Lawson1999a)



  • This organism has been recovered from clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Lawson1999a);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 6.5% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 10℃; doesn't grow at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; trehalose;
  • Active enzymes:
  • alkaline phosphatase; Gly-Trp arylamidase; Leu arylamidase; pyroGlu arylamidase; pyrrolidine arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • esterase C4; esterase lipase C8;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • VP test:
  • not active
  • Haemolysis:
  • alpha
    • RESPONSE TO ANTIBIOTICS
    Class Active Resistant
  • Penicillins:
  • amoxicillin; meropenem; penicillin;
  • Macrolides:
  • quinupristin-dalfopristin;
  • Quinolines:
  • levofloxacin; trovafloxacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Aerococcaceae Genus:  Facklamia Gram stain:  + O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Oval-shaped
    Health:  Unknown
    Source:  clinical sources
    Opt. T:  37℃
    Low T(℃):  10(neg)
    High T(℃):  45(neg)
    NaCl >6%:  6.5(+)
    		Urea:  neg Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Glucose:  + Ribose:  neg D-Tagatose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  + Glycogen:  neg D-Arabitol:  neg Mannitol:  neg Sorbitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg α-Mannosidase:  neg β-Mannosidase:  neg ArgDH:  neg Chymotrypsin:  neg Trypsin:  neg AlaPheProAA:  neg CystineAA:  neg GlyTrpAA:  + LeuAA:  + PyrrolidAA:  + PyrogluAA:  + AlkalineP:  + AcidP:  neg Esterase(C4):  d EstLip(C8):  d Lipase(C14):  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  SensRNG: (0.03-0.25)
    penicillin:  SensRNG: (0.03-0.5)
    meropenem:  SensRNG: (0.06-2)
    cefotaxime:  Var(MIC50): 0.06-4), MIC90: Var(0.06-4
    cefuroxime:  Var(MIC50): 0.12-8), MIC90: Var(0.12-8
    erythromycin:  Var(MIC50): 0.06-16), MIC90: Var(0.06-16
    quin-dalf:  SensRNG: (1-4)
    levofloxacin:  SensRNG: (0.5-4)
    trovafloxacin:  SensRNG: (0.25-0.5)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  SensRNG: (0.12-1)
    rifampicin:  SensRNG: (1-4)
    chloramphenicol:  SensRNG: (2-8)
    SXT:  Var(MIC50): 0.12-8), MIC90: Var(0.12-8
    clindamycin:  SensRNG: (0.06-2)

    References

    SPECIFIC REFERENCES FOR FACKLAMIA LANGUIDA
  • Lawson1999a - Facklamia languida sp. nov., isolated from human clinical specimens.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR FACKLAMIA LANGUIDA
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: February 09, 2022