Fastidiosipila sanguinis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Fastidiosipila sanguinis is a Gram-positive, non-spore-forming, microaerophilic, non-motile, coccus bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 32.9%. Fastidiosipila sanguinis is probably a rare gut coloniser. (Falsen2005)



  • This organism has been recovered from human blood. It is an opportunistic pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Falsen2005);
    Character Response
  • Substrates hydrolysed or digested:
  • hippurate;
  • Active enzymes:
  • Ala-Phe-Pro arylamidase; Arg arylamidase; N-Ac β-glucosaminidase; fucosidase; α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; β-mannosidase; Pro arylamidase;
  • ±
  • Strain-dependent active enzymes:
  • Gly arylamidase; His arylamidase; Ser arylamidase; Tyr arylamidase;
    • SPECIAL FEATURES (Falsen2005);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (minor); butyrate (minor);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Falsen2005);
    Class Active Resistant
  • Aminoglycosides:
  • kanamycin;
  • Heterocycles:
  • metronidazole;
  • Vancomycins:
  • vancomycin;
  • Miscellaneous antibiotics:
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Oscillospiraceae Genus:  Fastidiosipila Gram stain:  + O2 Relation.:  microaerophilic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  human blood
    DNA G+C(%):  32.9
    		Urea:  neg Gelatin:  neg Hippurate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Arab:  neg Ac-β-glcamnd:  + α-Fucosidase:  + α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg β-Mannosidase:  + ArgDH:  neg GluDC:  neg AlanineAA:  w AlaPheProAA:  + ArgAA:  + GluGluAA:  neg GlyTrpAA:  neg GlyAA:  d HisAA:  d LeuAA:  w LeuGlyAA:  neg ProAA:  + PheAA:  neg PyrogluAA:  neg SerAA:  d TyrAA:  d AlkalineP:  neg Lecithinase:  neg Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  minor(+) Butyrate:  minor(+) Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  S(1000; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    vancomycin:  S(5; disc)
    metronidazole:  R(5; disc)
    colistin:  R(10; disc)

    References

    SPECIFIC REFERENCES FOR FASTIDIOSIPILA SANGUINIS
  • Falsen2005 - Fastidiosipila sanguinis gen. nov., sp. nov., a new Gram-positive, coccus-shaped organism from human blood.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR FASTIDIOSIPILA SANGUINIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • ...............................
    • Added: January 14, 2022