Fournierella massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Fournierella massiliensis is a Gram-negative, non-spore-forming, strictly anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 56.8%. Fournierella massiliensis is a common gut coloniser. (Togo2017)



  • This organism has been recovered from human faeces. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • In 90% of Europeans (unseenbio.com).
    • GENERAL CHARACTERISTICS (Togo2017);
    Character Response
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0-8.0; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • fructose; galactose; glucose; mannose; aesculin; lactose; maltose; melezitose; melibiose; raffinose; sucrose; D-turanose; glycerol; 5-ketogluconate; α-methyl glucoside; salicin;
  • ⥅
  • Substrates assimilated or utilised:
  • maltose; mannose;
  • Active enzymes:
  • acid phosphatase; N-Ac β-glucosaminidase; esterase C4; esterase lipase C8; α-galactosidase; α-glucosidase; β-glucosidase;
    • SPECIAL FEATURES (Togo2017);
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (major); propionate (minor); butyrate (minor); isobutyrate (minor);
  • ✗
  • Metabolites not produced:
  • indole;
  • ✓
  • Nitrate:
  • reduced
    • RESPONSE TO ANTIBIOTICS (Togo2017);
    Class Active Resistant
  • Penicillins:
  • amoxicillin; amoxicillin-clavulanic acid; imipenem; oxacillin; penicillin G;
  • Cephalosporins:
  • cefalexin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • gentamicin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole; nitrofurantoin; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Oscillospiraceae Genus:  Fournierella Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod
    Health:  Unknown
    Source:  human faeces
    DNA G+C(%):  56.8
    Opt. T:  37℃
    pH 6.0-8.0:  6.0-8.0(+)
    pH >8:  8.5(+)
    		Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  neg Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  + Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  + Maltose:  + Melezitose:  + Melibiose:  + Sucrose:  + Trehalose:  neg Turanose:  + Amygdalin:  neg Aesculin:  + Glycogen:  neg Inulin:  neg Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  + Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  + Me-α-D-Glc:  + Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg Salicin:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Mannose:  + Maltose:  + Mannitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Ac-β-glcamnd:  + α-Fucosidase:  neg α-Galactosidase:  + β-Galactosidase:  neg α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  neg α-Mannosidase:  neg Chymotrypsin:  neg Trypsin:  neg CystineAA:  neg LeuAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  Major(+) Propionate:  minor(+) Butyrate:  minor(+) Isobutyrate:  minor(+) Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Sens
    Augmentin:  Sens
    oxacillin:  Sens
    penicillin_G:  Sens
    imipenem:  Sens
    cefalexin:  Sens
    gentamicin:  Sens
    tobramycin:  Sens
    erythromycin:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    metronidazole:  Sens
    nitrofurantoin:  Sens
    SXT:  Sens

    References

    SPECIFIC REFERENCES FOR FOURNIERELLA MASSILIENSIS
  • Togo2017 - Fournierella massiliensis gen. nov., sp. nov., a new human-associated member of the family Ruminococcaceae.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR FOURNIERELLA MASSILIENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • GENERAL REFERENCES FOR FOURNIERELLA MASSILIENSIS
  • Ludwig2009 - Revised road map to the phylum Firmicutes.
    • Added: July 12, 2021