Fretibacterium fastidiosum

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Fretibacterium fastidiosum is a Gram-negative, non-spore-forming, strictly anaerobic, motile, rod-shaped - curved bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 63%. Fretibacterium fastidiosum is probably a rare gut coloniser.



  • This organism has been recovered from the human oral cavity. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • QUIRKS
  • Asaccharolytic. Growth stimulated by the presence of Fusobacterium nucleatum subsp. nucleatum.
    • GENERAL CHARACTERISTICS
    Character Response
  • pH
  • Acidity tolerance:
  • doesn't tolerate pH 5; doesn't tolerate pH 9; Grows optimally at pH 6-7.
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; grows at 42℃; Grows optimally at 37℃.
  • Active enzymes:
  • acid phosphatase; chymotrypsin; esterase C4; esterase lipase C8; Gly arylamidase; Leu-Gly arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES
    Character Response
  • ✓
  • Metabolites produced:
  • acetate (major); propionate; Hâ‚‚S;
  • ✗
  • Nitrate:
  • not reduced
  • Pigments:
  • yellow

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Synergistetes Class:  Synergistia Order:  Synergistales Family:  Synergistaceae Genus:  Fretibacterium Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Rod - curved Pigment:  yellow
    Health:  Unknown
    Source:  the human oral cavity
    DNA G+C(%):  63
    Opt. T:  37℃
    Lower T(℃):  25(+)
    High T(℃):  42(+)
    Opt. pH:  6-7
    pH 4.2-5.9:  5(neg)
    pH >8:  9(neg)
    		Aesculin:  neg Urea:  neg Gelatin:  w Arginine:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Fructose:  neg Galactose:  neg Glucose:  neg Lactose:  neg Maltose:  neg Sucrose:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Chymotrypsin:  + GlyAA:  + LeuGlyAA:  + AcidP:  + Esterase(C4):  + EstLip(C8):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Acetate:  Major(+) Propionate:  + H2S:  + Pigment:  yellow

    References

    SPECIFIC REFERENCES FOR FRETIBACTERIUM FASTIDIOSUM
  • Vartoukian2013 - Fretibacterium fastidiosum gen. nov., sp. nov., isolated from the human oral cavity.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR FRETIBACTERIUM FASTIDIOSUM
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    • Added: October 10, 2022