Gabonibacter massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Gabonibacter massiliensis is a Gram-negative, non-spore-forming, strictly anaerobic, motile, coccobacillus bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 42.1%. Gabonibacter massiliensis is probably a common, although minor, coloniser of the gut. (Mourembou2016a)



  • This organism has been recovered from human faeces (Bilen2018e) and clinical specimens (blood - CCUG). Can cause opportunistic infections, particularly in immunocompromised people. A possible gut commensal.
    • QUIRKS
  • In 31% of Europeans (unseenbio.com). Minor coloniser.
    • GENERAL CHARACTERISTICS (Mourembou2016a);
    Character Response
  • Substrates hydrolysed or digested:
  • gelatin;
  • 🧂
  • Salt tolerance:
  • tolerates 0% salt; tolerates 5% salt;
  • pH
  • Acidity tolerance:
  • tolerates pH 6.0; tolerates pH 8.5;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 45℃; Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • glucose; ribose; D-tagatose; trehalose; 5-ketogluconate;
  • ⥅
  • Substrates assimilated or utilised:
  • mannitol; salicin; trehalose;
  • Active enzymes:
  • acid phosphatase; esterase C4; esterase lipase C8; naphthol-ASBI-P;
    • SPECIAL FEATURES (Mourembou2016a);
    Character Response
  • ✓
  • Metabolites produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Mourembou2016a);
    Class Active Resistant
  • Penicillins:
  • imipenem;
  • amoxicillin; amoxicillin-clavulanic acid;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Aminoglycosides:
  • amikacin; gentamicin; tobramycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • metronidazole; nitrofurantoin;
  • trimethoprim-sulfamethoxazole;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Bacteroidetes Class:  Bacteroidia Order:  Bacteroidales Family:  Porphyromonadaceae Genus:  Gabonibacter Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Swimming Morphology:  Coccobacillus
    Health:  Unknown
    Source:  human faeces (Bilen2018e) and clinical specimens (blood - CCUG)
    DNA G+C(%):  42.1
    Opt. T:  37℃
    High T(℃):  45(neg)
    NaCl 0.5-2%:  0(+)
    NaCl 3-5%:  5(+)
    pH 6.0-8.0:  6.0(+)
    pH >8:  8.5(+)
    		Urea:  neg Gelatin:  +
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  neg Glucose:  + Mannose:  neg Ribose:  + D-Tagatose:  + Lactose:  neg Maltose:  neg Sucrose:  neg Trehalose:  + 5-Ketogluconate:  +
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    L-Arabinose:  neg Glucose:  neg Mannose:  neg Rhamnose:  neg Xylose:  neg Cellubiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Raffinose:  neg Sucrose:  neg Trehalose:  + Aesculin:  neg Glycerol:  neg Mannitol:  + Salicin:  + Sorbitol:  neg Trp:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg β-Glucuronidase:  neg Chymotrypsin:  neg Trypsin:  neg CystineAA:  neg LeuAA:  neg ValAA:  neg AlkalineP:  neg AcidP:  + Esterase(C4):  + EstLip(C8):  + Lipase(C14):  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    amoxicillin:  Res
    Augmentin:  Res
    imipenem:  Sens
    amikacin:  Res
    gentamicin:  Res
    tobramycin:  Res
    erythromycin:  Res
    ciprofloxacin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Res
    rifampicin:  Res
    metronidazole:  Sens
    nitrofurantoin:  Sens
    SXT:  Res
    clindamycin:  Res

    References

    SPECIFIC REFERENCES FOR GABONIBACTER MASSILIENSIS
  • Mourembou2016a - Description of Gabonibacter massiliensis gen. nov., sp. nov., a New Member of the Family Porphyromonadaceae Isolated from the Human Gut Microbiota.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR GABONIBACTER MASSILIENSIS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • ...............................
    • GENERAL REFERENCES FOR GABONIBACTER MASSILIENSIS
  • Bilen2018e - Description of the human gut microbiota by culturomics
    • Added: January 06, 2022