Globicatella sulfidifaciens

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Globicatella sulfidifaciens is a Gram-variable, non-spore-forming, facultatively anaerobic, non-motile, coccus bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 35-36%. Globicatella sulfidifaciens is probably a rare gut coloniser. (Vandamme2001a)



  • This organism has been recovered from animal wounds. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: animal pathogen). Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Vandamme2001a);
    Character Response
  • Substrates hydrolysed or digested:
  • aesculin;
  • 🧂
  • Salt tolerance:
  • tolerates 6.5% salt;
  • 💧
  • Bile tolerance:
  • Doesn't tolerate bile
  • 🌡
  • Temperature tolerance:
  • grows at 25℃; Grows optimally at 37-42℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; fructose; glucose; mannose; xylose; aesculin; glycogen; inulin; cellubiose; maltose; melibiose; raffinose; sucrose; trehalose; arbutin;
  • Active enzymes:
  • α-galactosidase; β-galactosidase; α-glucosidase; β-glucosidase; β-glucuronidase; Leu arylamidase; Phe arylamidase; Pro arylamidase; pyroGlu arylamidase;
    • SPECIAL FEATURES (Vandamme2001a);
    Character Response
  • ✓
  • Metabolites produced:
  • H₂S;
  • ✗
  • VP test:
  • not active
  • Haemolysis:
  • alpha
    • RESPONSE TO ANTIBIOTICS (Vandamme2001a);
    Class Active Resistant
  • Macrolides:
  • erythromycin;
  • Aminoglycosides:
  • neomycin;
  • Miscellaneous antibiotics:
  • clindamycin; lincomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Bacilli Order:  Lactobacillales Family:  Aerococcaceae Genus:  Globicatella Gram stain:  vr O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  animal wounds
    DNA G+C(%):  35-36
    Opt. T:  37-42℃
    Lower T(℃):  25(+)
    NaCl >6%:  6.5(+)
    Bile reaction(%):  neg
    		Aesculin:  + Starch:  w Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  + Fructose:  + Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  + Mannose:  + Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  + L-Xylose:  neg Cellubiose:  + Gentiobiose:  neg Maltose:  + Melezitose:  neg Melibiose:  + Sucrose:  + Trehalose:  + Turanose:  neg Amygdalin:  neg Aesculin:  + Glycogen:  + Inulin:  + Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  + Gluconate:  neg 2-Ketogluconate:  neg 5-Ketogluconate:  neg Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Catalase:  neg Urease:  neg α-Galactosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + β-Glucuronidase:  + ArgDH:  neg ArgAA:  neg LeuAA:  + ProAA:  + PyrrolidAA:  neg PheAA:  + PyrogluAA:  + ValAA:  neg AlkalineP:  neg AcidP:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  +
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    neomycin:  Res
    erythromycin:  Res
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    clindamycin:  Res
    lincomycin:  Res

    References

    SPECIFIC REFERENCES FOR GLOBICATELLA SULFIDIFACIENS
  • Vandamme2001a - Globicatella sulfidifaciens sp. nov., isolated from purulent infections in domestic animals.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR GLOBICATELLA SULFIDIFACIENS
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022