Helicobacter felis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Helicobacter felis is a Gram-negative, non-spore-forming, microaerophilic, motile, helical-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 42.5%. Helicobacter felis is unlikely to be a gut coloniser. (Paster1991)



  • This organism has been recovered from the gastic mucosa of a cat. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: human and animal pathogen). Is a known human pathogen. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Paster1991);
    Character Response
  • Substrates hydrolysed or digested:
  • urea;
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 1.5% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 25℃; grows at 37℃; grows at 42℃;
  • Active enzymes:
  • alkaline phosphatase; Arg arylamidase; catalase; γ-Glu transferase; His arylamidase; Leu arylamidase; oxidase;
    • SPECIAL FEATURES (Paster1991);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S; indole;
  • ±
  • Nitrate:
  • reduced by most strains
    • RESPONSE TO ANTIBIOTICS (Paster1991);
    Class Active Resistant
  • Penicillins:
  • ampicillin;
  • Cephalosporins:
  • cephalothin;
  • Macrolides:
  • erythromycin;
  • Quinolines:
  • nalidixic-acid;
  • Heterocycles:
  • metronidazole;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Epsilonproteobacteria Order:  Campylobacterales Family:  Helicobacteraceae Genus:  Helicobacter Gram stain:  neg O2 Relation.:  microaerophilic Spore:  No spore Motility:  Swimming Morphology:  Helical
    Health:  Unknown
    Source:  the gastic mucosa of a cat
    DNA G+C(%):  42.5
    Lower T(℃):  25(neg)
    Mid T(℃):  37(+)
    High T(℃):  42(+)
    NaCl 0.5-2%:  1.5(neg)
    		Urea:  + Hippurate:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    Arabinose:  neg Fructose:  neg Galactose:  neg Glucose:  neg Xylose:  neg Lactose:  neg Maltose:  neg Sucrose:  neg Sorbitol:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + α-Arab:  neg Ac-β-glcamnd:  neg α-Fucosidase:  neg α-Galactosidase:  neg β-Galactosidase:  neg α-Glucosidase:  neg β-Glucosidase:  neg β-Glucuronidase:  neg ArgDH:  neg γ-Glu transf.:  + AlanineAA:  neg ArgAA:  + GlyAA:  neg HisAA:  + LeuAA:  + ProAA:  neg PheAA:  neg PyrogluAA:  neg TyrAA:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Sens
    cephalothin:  S(30; disc)
    erythromycin:  Sens
    nalidixic-acid:  R(30; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    metronidazole:  Sens

    References

    SPECIFIC REFERENCES FOR HELICOBACTER FELIS
  • Paster1991 - Phylogeny of Helicobacter felis sp. nov., Helicobacter mustelae, and related bacteria.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR HELICOBACTER FELIS
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • Added: January 14, 2022