Helicobacter fennelliae

(aka Campylobacter fennelliae)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Helicobacter fennelliae, (aka Campylobacter fennelliae), is a Gram-negative, non-spore-forming, microaerophilic, motile, helical-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 37-38%. Helicobacter fennelliae is probably a rare gut coloniser. (TrivettMoore1997; On2005Bergey; Vandamme1991a; On2005Bergey; Totten1985)



  • This organism has been recovered from human faeces (CCUG) and clinical sources. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread. Is a rare opportunistic pathogen. A possible gut commensal. Robust growth can have negative consequences for gut health.
    • GENERAL CHARACTERISTICS (TrivettMoore1997); (On2005Bergey); (Vandamme1991a); (On2005Bergey); (Totten1985);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 2% salt;
  • 🌡
  • Temperature tolerance:
  • doesn't grow at 25℃; strain-variable at 42(d); Grows optimally at 37℃.
  • Active enzymes:
  • alkaline phosphatase; catalase; γ-Glu transferase; leucine aminopeptidase; oxidase;
    • SPECIAL FEATURES (On2005Bergey);
    Character Response
  • ✗
  • Metabolites not produced:
  • H₂S;
  • ✗
  • VP test:
  • not active
  • ✗
  • Nitrate:
  • not reduced
  • ✗
  • Pigments:
  • not produced
    • RESPONSE TO ANTIBIOTICS (TrivettMoore1997); (On2005Bergey); (Vandamme1991a); (On2005Bergey); (Totten1985);
    Class Active Resistant
  • Penicillins:
  • ampicillin;
  • Cephalosporins:
  • cefoxitin;
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • doxycycline; tetracycline;
  • Quinolines:
  • nalidixic-acid;
  • Aminoglycosides:
  • gentamicin; spectinomycin;
  • streptomycin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • chloramphenicol; metronidazole; sulfamethoxazole; trimethoprim-sulfamethoxazole;
  • trimethoprim;
  • Miscellaneous antibiotics:
  • clindamycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Epsilonproteobacteria Order:  Campylobacterales Family:  Helicobacteraceae Genus:  Helicobacter Alt. name:  Campylobacter fennelliae Gram stain:  neg O2 Relation.:  microaerophilic Spore:  No spore Motility:  Swimming Morphology:  Helical Pigment:  neg
    Health:   Negative
    Source:  human faeces (CCUG) and clinical sources
    DNA G+C(%):  37-38
    Opt. T:  37℃
    Lower T(℃):  25(neg)
    High T(℃):  42(d)
    NaCl 0.5-2%:  2(neg)
    		Urea:  neg Gelatin:  neg Starch:  neg Casein:  neg Tyrosine:  neg Hippurate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + Urease:  neg γ-Glu transf.:  + LeuAP:  d(+) GlyAA:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		H2S:  neg Pigment:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    ampicillin:  Sens
    cefoxitin:  S(30)
    gentamicin:  Sens
    spectinomycin:  Sens
    streptomycin:  Res
    erythromycin:  Sens
    nalidixic-acid:  S(30)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Sens
    tetracycline:  Sens
    rifampicin:  Sens
    chloramphenicol:  Sens
    metronidazole:  Sens
    sulfamethoxazole:  S(<4)
    trimethoprim:  Res
    SXT:  S(<8)
    clindamycin:  Sens

    References

    SPECIFIC REFERENCES FOR HELICOBACTER FENNELLIAE
  • TrivettMoore1997 - Helicobacter westmeadii sp. nov., a new species isolated from blood cultures of two AIDS patients.
  • On2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Helicobacteraceae, Genus I. Helicobacter
  • Vandamme1991a - Revision of Campylobacter, Helicobacter, and Wolinella Taxonomy: Emendation of Generic Descriptions and Proposal of Arcobacter gen. nov.
  • On2005Bergey - Bergey's manual of systematic bacteriology. Vol. 2, The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Helicobacteraceae, Genus I. Helicobacter
  • Totten1985 - Campylobacter cinaedi (sp. nov.) and Campylobacter fennelliae (sp, nov.): Two New Campylobacter Species Associated with Enteric Disease in Homosexual Men.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR HELICOBACTER FENNELLIAE
  • Lagier2016 - Culture of previously uncultured members of the human gut microbiota by culturomics.
  • ...............................
    • GENERAL REFERENCES FOR HELICOBACTER FENNELLIAE
  • CCUG - Culture Collection University of Gothenburg - Entire Collection
    • Added: July 12, 2021