Heliomicrobium modesticaldum

(aka Heliobacterium modesticaldum)

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Heliomicrobium modesticaldum, (aka Heliobacterium modesticaldum), is a Gram-negative, spore-forming, strictly anaerobic, variably-motile, rod-shaped - curved bacterium. It has been detected in at least 2 gut microbiome compilation studies or metastudies. The DNA G+C content is 54.6-55%. Heliomicrobium modesticaldum is likely to be transient and not a long-term gut coloniser. (Kimble1995)



  • This organism has been recovered from neutral or alkaline hot springs, Iceland. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. Likely to be transient and not a long-term gut commensal.
    • QUIRKS
  • Grows phototrophically by photoassimilating pyruvate, lactate and acetate. High optimum growth temperature so unlikely to be a gut coloniser.
    • GENERAL CHARACTERISTICS (Kimble1995);
    Character Response
  • 🧂
  • Salt tolerance:
  • doesn't tolerate 1% salt; Grows optimally with 0% salt.
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 6-7.
  • 🌡
  • Temperature tolerance:
  • grows at 30℃; grows at 56℃; Grows optimally at 52℃.
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  • Substrates assimilated or utilised:
  • cysteine; methionine; acetate; lactate; pyruvate; N2 fixed; NH4+ consumed;
    • SPECIAL FEATURES (Kimble1995);
    Character Response
  • Thiosulfate:
  • source of sulfur

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Firmicutes Class:  Clostridia Order:  Eubacteriales Family:  Heliobacteriaceae Genus:  Heliomicrobium Alt. name:  Heliobacterium modesticaldum Gram stain:  neg O2 Relation.:  strictly anaerobic Spore:  Endospore Motility:  vr Morphology:  Rod - curved
    Health:  Unknown
    Source:  neutral or alkaline hot springs, Iceland
    DNA G+C(%):  54.6-55
    Opt. T:  52℃
    Lower T(℃):  30(+)
    High T(℃):  56(+)
    NaCl 0.5-2%:  1(neg)
    Opt. pH:  6-7
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Cys:  + Met:  + Acetate:  + Lactate:  + Pyruvate:  +

    References

    SPECIFIC REFERENCES FOR HELIOMICROBIUM MODESTICALDUM
  • Kyndt2021 - Phylogenetic relationship of phototrophic heliobacteria and systematic reconsideration of species and genus assignments based on genome sequences of eight species.
  • Kimble1995 - Heliobacterium modesticaldum, sp. nov., a thermophilic heliobacterium of hot springs and volcanic soils.
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    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR HELIOMICROBIUM MODESTICALDUM
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
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    • Added: March 18, 2022