Histophilus somni

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Histophilus somni is a Gram-negative, non-spore-forming, facultatively anaerobic, non-motile, rod-shaped bacterium. It has been detected in at least 3 gut microbiome compilation studies or metastudies. The DNA G+C content is 37.5%. Histophilus somni is probably a rare gut coloniser. (Angen2003)



  • This organism has been recovered from cattle and sheep infections. The risk classification (www.baua.de) for this organism is 2, i.e., risk of individual infection, but low risk of spread (notes: opportunistic in immunocompromised patients). Could be a possible pathogen in humans, but unknown at this stage. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Angen2003);
    Character Response
  • H+
  • Acid from carbohydrates usually produced:
  • glucose;
  • ±
  • Strain-dependent acid from carbs:
  • mannose;
  • ⥅
  • Substrates assimilated or utilised:
  • CO2 consumed;
  • Active enzymes:
  • alkaline phosphatase; β-galactosidase; oxidase;
    • SPECIAL FEATURES (Angen2003);
    Character Response
  • ✓
  • Metabolites produced:
  • indole (most strains);
  • ✗
  • VP test:
  • not active
  • ±
  • Haemolysis:
  • strain dependent
  • ✓
  • Nitrate:
  • reduced
  • Pigments:
  • yellow

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Gammaproteobacteria Order:  Pasteurellales Family:  Pasteurellaceae Genus:  Histophilus Gram stain:  neg O2 Relation.:  facultatively anaerobic Spore:  No spore Motility:  Sessile Morphology:  Rod Pigment:  yellow
    Health:  Unknown
    Source:  cattle and sheep infections
    DNA G+C(%):  37.5
    		Urea:  neg Gelatin:  neg
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    L-Arabinose:  neg Fructose:  neg Galactose:  neg Glucose:  + Mannose:  d Rhamnose:  neg Sorbose:  neg Xylose:  neg Maltose:  neg Sucrose:  neg Trehalose:  neg Aesculin:  neg Adonitol:  neg Dulcitol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Salicin:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    Citrate:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  neg Urease:  neg β-Galactosidase:  + ArgDH:  neg LysDC:  neg OrnDC:  neg AlkalineP:  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  d(+) Pigment:  yellow

    References

    SPECIFIC REFERENCES FOR HISTOPHILUS SOMNI
  • Angen2003 - Proposal of Histophilus somni gen. nov., sp. nov. for the three species incertae sedis 'Haemophilus somnus', 'Haemophilus agni' and 'Histophilus ovis'.
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR HISTOPHILUS SOMNI
  • Byrd2020 - Stability and dynamics of the human gut microbiome and its association with systemic immune traits.
  • New2022 - Collective effects of human genomic variation on microbiome function.
  • Zeller2014 - Potential of fecal microbiota for early-stage detection of colorectal cancer
  • ...............................
    • Added: March 18, 2022