Hugonella massiliensis

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Hugonella massiliensis is a Gram-positive, non-spore-forming, strictly anaerobic, non-motile, coccus bacterium. The DNA G+C content is 63.5%. Hugonella massiliensis is probably a rare gut coloniser. (Elsawi2017)



  • This organism has been recovered from human faeces (obese). Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Elsawi2017);
    Character Response
  • 🧂
  • Salt tolerance:
  • tolerates 1.5% salt; Grows optimally with 0-0.5% salt.
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 7.
  • 🌡
  • Temperature tolerance:
  • Grows optimally at 37℃.
  • H+
  • Acid from carbohydrates usually produced:
  • L-arabinose; mannose; amygdalin; aesculin; inulin; 2-ketogluconate; 5-ketogluconate; N-Ac glucosamine;
  • Active enzymes:
  • chymotrypsin; esterase C4; esterase lipase C8; fucosidase; β-galactosidase; α-glucosidase; β-glucosidase; Leu arylamidase; lipase C14; α-mannosidase; trypsin; Val arylamidase; naphthol-ASBI-P;
    • SPECIAL FEATURES
    Character Response
  • ✗
  • Metabolites not produced:
  • indole;
  • ✗
  • Nitrate:
  • not reduced
    • RESPONSE TO ANTIBIOTICS (Elsawi2017);
    Class Active Resistant
  • Penicillins:
  • oxacillin; penicillin;
  • Cephalosporins:
  • cefoxitin;
  • Macrolides:
  • pristinamycin;
  • erythromycin;
  • Tetracyclines:
  • doxycycline;
  • Quinolines:
  • ciprofloxacin;
  • Polypep/ketides:
  • rifampicin;
  • Heterocycles:
  • fosfomycin; metronidazole; trimethoprim-sulfamethoxazole;
  • Vancomycins:
  • vancomycin; teicoplanin;
  • Miscellaneous antibiotics:
  • clindamycin; linezolid; pristinamycin;
  • colistin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Actinobacteria Class:  Coriobacteriia Order:  Eggerthellales Family:  Eggerthellaceae Genus:  Hugonella Gram stain:  + O2 Relation.:  strictly anaerobic Spore:  No spore Motility:  Sessile Morphology:  Coccus
    Health:  Unknown
    Source:  human faeces (obese)
    DNA G+C(%):  63.5
    Opt. T:  37℃
    NaCl 0.5-2%:  1.5(+)
    Opt. pH:  7
    CARBOHYDRATE ACID FORMATION
    Monosaccharide O/F Oligosaccharide O/F Polysaccharide O/F Polyol O/F Other O/F
    D-Arabinose:  neg L-Arabinose:  + Fructose:  neg Fucose:  neg D-Fucose:  neg Galactose:  neg Glucose:  neg Mannose:  + D-Lyxose:  neg Rhamnose:  neg Ribose:  neg Sorbose:  neg D-Tagatose:  neg Xylose:  neg L-Xylose:  neg Cellubiose:  neg Gentiobiose:  neg Lactose:  neg Maltose:  neg Melezitose:  neg Melibiose:  neg Sucrose:  neg Trehalose:  neg Turanose:  neg Amygdalin:  + Aesculin:  + Glycogen:  neg Inulin:  + Starch:  neg Adonitol:  neg D-Arabitol:  neg L-Arabitol:  neg Dulcitol:  neg Erythritol:  neg Glycerol:  neg Inositol:  neg Mannitol:  neg Sorbitol:  neg Xylitol:  neg Arbutin:  neg Gluconate:  neg 2-Ketogluconate:  + 5-Ketogluconate:  + Me-α-D-Glc:  neg Me-α-D-Mann:  neg Me-Xyloside:  neg NAc-α-GA:  + Salicin:  neg
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  neg Catalase:  neg Urease:  neg α-Fucosidase:  + β-Galactosidase:  + α-Glucosidase:  + β-Glucosidase:  + α-Mannosidase:  + Chymotrypsin:  + Trypsin:  + LeuAA:  + ValAA:  + AlkalineP:  neg Esterase(C4):  + EstLip(C8):  + Lipase(C14):  +
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Indole:  neg
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    oxacillin:  Sens
    penicillin:  Sens
    cefoxitin:  Sens
    erythromycin:  Res
    pristinamycin:  Sens
    linezolid:  Sens
    ciprofloxacin:  Sens
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    doxycycline:  Res
    teicoplanin:  Sens
    vancomycin:  Sens
    rifampicin:  Sens
    fosfomycin:  Sens
    metronidazole:  Sens
    SXT:  Sens
    clindamycin:  Sens
    colistin:  Res

    References

    SPECIFIC REFERENCES FOR HUGONELLA MASSILIENSIS
  • Elsawi2017 - Hugonella massiliensis gen. nov., sp. nov., genome sequence, and description of a new strictly anaerobic bacterium isolated from the human gut.
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    • Added: April 08, 2023