Hyphomicrobium facile

Bacteria
General | Carbohydrate O/F | Substrate utilisation | Enzymes | Metabolites | Antibiotics

Overview

  • Hyphomicrobium facile is a Gram-negative, non-spore-forming, aerobic, motile, oval-shaped bacterium. It has been detected in at least 1 gut microbiome compilation study or metastudy. The DNA G+C content is 60%. Hyphomicrobium facile is probably a rare gut coloniser. (Gliesche2005)



  • This organism has been recovered from human faeces and soil. The risk classification (www.baua.de) for this organism is 1, i.e., low risk of infection and spread. Pathogenicity status unknown, or very unlikely to be pathogenic. A possible gut commensal.
    • GENERAL CHARACTERISTICS (Gliesche2005);
    Character Response
  • 🧂
  • Salt tolerance:
  • grows weakly in 3.5% salt;
  • pH
  • Acidity tolerance:
  • Grows optimally at pH 6.5-7.
  • 🌡
  • Temperature tolerance:
  • grows at 5℃; grows at 37℃; doesn't grow at 45℃;
  • ⥅
  • Substrates assimilated or utilised:
  • N-acetylglucosamine; glycerol; methanol; leucine; lysine; phenylalanine; butyrate; formate; 3-hydroxybutyrate; lactate; oxalate; succinate;
  • Active enzymes:
  • catalase; oxidase;
    • SPECIAL FEATURES (Gliesche2005);
    Character Response
  • ✗
  • Haemolysis:
  • absent
  • ✓
  • Nitrate:
  • reduced
  • Pigments:
  • brown
    • RESPONSE TO ANTIBIOTICS (Gliesche2005);
    Class Active Resistant
  • Macrolides:
  • erythromycin;
  • Tetracyclines:
  • tetracycline;
  • Aminoglycosides:
  • kanamycin; neomycin; streptomycin;

    • Details

    GENERAL
    Lineage Physiology General Growth Tolerances Hydrol./digest./degr.
    Phylum:  Proteobacteria Class:  Alphaproteobacteria Order:  Hyphomicrobiales Family:  Hyphomicrobiaceae Genus:  Hyphomicrobium Gram stain:  neg O2 Relation.:  aerobic Spore:  No spore Motility:  Swimming Morphology:  Oval-shaped Pigment:  brown
    Health:  Unknown
    Source:  human faeces and soil
    DNA G+C(%):  60
    Low T(℃):  5(+)
    Mid T(℃):  37(+)
    High T(℃):  45(neg)
    NaCl 3-5%:  3.5(w)
    Opt. pH:  6.5-7
    pH 6.0-8.0:  7.0
    		Gelatin:  neg Milk:  neg
    SUBSTRATE ASSIMILATION & UTILISATION
    Monosaccharide util/assim Oligosaccharide util/assim Other carboh. util/assim Amino acid util/assim Organic acid util/assim
    N_Acetyl_glucosamine:  + Amygdalin:  w Ethanol:  w Glycerol:  + Methanol:  + Leu:  + Lys:  + Phe:  + Acetate:  w Butyrate:  + Formate:  + 3-Hydroxybutyrate:  + Lactate:  + Succinate:  +
    ENZYME ACTIVITY
    Enzymes: General Enzymes: Carbohydrate Enzymes: Protein Enzymes: Arylamidases Enzymes: Esters/fats
    Oxidase:  + Catalase:  + LysDC:  neg
    METABOLITES - PRODUCTION & USE
    Fuel Usable Metabolites Metabolites Released Special Products Compounds Produced

    		Pigment:  brown
    ANTIBIOTICS ℞
    Penicillins & Penems (μg/mL) Cephalosporins (μg/mL) Aminoglycosides (μg/mL) Macrolides (μg/mL) Quinolones (μg/mL)
    kanamycin:  S(30; disc)
    neomycin:  S(30; disc)
    streptomycin:  S(10; disc)
    erythromycin:  S(30; disc)
    Tetracyclines (μg/mL) Vancomycin Class (μg/mL) Polypep/ketides (μg/mL) Heterocycles (μg/mL) Other (μg/mL)
    tetracycline:  S(30; disc)

    References

    SPECIFIC REFERENCES FOR HYPHOMICROBIUM FACILE
  • Gliesche2005 - Bergey's manual of systematic bacteriology. Vol. 2, The The Alpha-, Beta-, Delta-, and Epsilonproteobacteria Part C. Family Hyphomicrobiaceae, Genus I. Hyphomicrobium
  • ...............................
    • GUT MICROBIOME COMPILATIONS AND METASTUDIES FOR HYPHOMICROBIUM FACILE
  • Yang2020 - Species-Level Analysis of Human Gut Microbiota With Metataxonomics.
  • Yang2020a - Establishing high-accuracy biomarkers for colorectal cancer by comparing fecal microbiomes in patients with healthy families
  • ...............................
    • Added: December 15, 2021